NCT02437929

Brief Summary

This study aims to assess self reported procedural pain compared with background pain and evaluate pain intensity differences across six standard procedures. Besides, rescue and preventive treatments used to control procedural pain will be examined.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,079

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2015

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 30, 2015

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 8, 2015

Completed
24 days until next milestone

Study Start

First participant enrolled

June 1, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
Last Updated

July 12, 2016

Status Verified

December 1, 2015

Enrollment Period

6 months

First QC Date

April 30, 2015

Last Update Submit

July 11, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • 11 Points - Numerical Rating Scale (NRS); change in baseline pain intensity during the procedure (of 3 points NRS or higher)

    Self reported pain intensity 10 minutes before the procedure, during the procedure (measured immediately after that the procedure is performed), 10 minutes after the procedure. Each item is scored 0-10 (0 = no pain; 10 = worst possible pain).

    Participants will be followed 10 minutes before the procedure, for the duration of the procedure and ten minutes after, an expected average of 1 hour

Study Arms (1)

Patients receiving standard procedures

Procedure: MobilizationProcedure: PositioningProcedure: Personal Hygiene CareProcedure: Bladder catheterizationProcedure: Wound careProcedure: Subcutaneous drugs administration

Interventions

MobilizationPROCEDURE
Patients receiving standard procedures
PositioningPROCEDURE
Patients receiving standard procedures
Patients receiving standard procedures
Patients receiving standard procedures
Wound carePROCEDURE
Patients receiving standard procedures
Patients receiving standard procedures

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Terminally ill patients, cancer and non-cancer, admitted in a palliative care service (inpatients or outpatients), that are undergoing at least one procedure considered in the study, as a part of their Individual Care Plan (ICP).

You may qualify if:

  • Patients receiving the procedures included in this study as a part of their standard care
  • Patients that have expressed their consent to participate to the study by signing the informed consent document

You may not qualify if:

  • Very serious or unstable clinical conditions with a Karnofsky Performance Status Index (KPS) \< 20
  • Presence of neurological or psychiatric conditions, due to the original disease or concomitant diseases, interfering with the patient's level of consciousness or with judgment, such as to compromise compliance with the study protocol;
  • Not adequately controlled background pain (average NRS in the last 24 hours is \> 4)
  • Emergency procedures or procedures performed during night time (from 8 p.m. until 8 a.m)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

San Marco hospice

Latina, Italy

Location

MeSH Terms

Conditions

Breakthrough PainPainNeoplasms

Interventions

Patient PositioningUrinary Catheterization

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and ServicesDiagnostic Techniques, UrologicalDiagnostic Techniques and ProceduresDiagnosisCatheterizationInvestigative Techniques

Study Officials

  • Giuseppe Casale, Medicine

    Antea Foundation

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 30, 2015

First Posted

May 8, 2015

Study Start

June 1, 2015

Primary Completion

December 1, 2015

Study Completion

April 1, 2016

Last Updated

July 12, 2016

Record last verified: 2015-12

Data Sharing

IPD Sharing
Will not share

Locations