NCT02431546

Brief Summary

The purpose of this study is to understand the effects of a mobile health cardiovascular prevention program in patients who have recently graduated from cardiac rehabilitation. The mobile health program will focus on promoting healthy lifestyles through the use of a mobile application (app), mobile physical activity monitor and a system of remote health coaching. By testing a novel mHealth intervention focused on lifestyle modification, this trial will address a critical evidence gap in the care of patients after they graduate from CR. Many patients who graduate from traditional CR struggle with unhealthy lifestyles, and these patients currently have no lifestyle-based care strategies to help them. The results of this study have the potential to lead to new sustainable and resource-efficient, lifestyle-based preventive care strategies for patients with stable CVD.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at below P25 for not_applicable coronary-artery-disease

Timeline
Completed

Started Jul 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 1, 2015

Completed
2 months until next milestone

Study Start

First participant enrolled

July 1, 2015

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 20, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 20, 2017

Completed
Last Updated

February 5, 2018

Status Verified

January 1, 2018

Enrollment Period

1.7 years

First QC Date

April 28, 2015

Last Update Submit

January 31, 2018

Conditions

Keywords

CardiologyVascularCADDukeCardiac RehabilitationPreventionCVDMobile HealthExercise

Outcome Measures

Primary Outcomes (1)

  • Change in fitness (peak VO2mL/kg/min) as measured by cardiopulmonary exercise test (CPET).

    peak VO2mL/kg/min

    Baseline and 14-weeks

Secondary Outcomes (7)

  • Understand the feasibility and implementation of this novel mhealth treatment strategy.

    14-weeks

  • Change in Physical Activity as measured using a Fitbit

    Baseline and 14-weeks

  • Change in Quality of Life (QOL) as measured by Seattle Angina Questionnaire (SAQ).

    Baseline and 14-weeks

  • Change in Medication Adherence as measured by Morisky Medication Adherence Scale (MMAS-8).

    Baseline and 14-weeks

  • Change in Body Mass

    Baseline and 14-weeks

  • +2 more secondary outcomes

Study Arms (2)

Mobile Health Application Group

EXPERIMENTAL

VIDA is a mobile technology that is well positioned to provide healthcare coaching. After completing the CR program, each participant will have access to the VIDA mobile phone platform for the 12-week intervention, and be instructed to download the app on his/her smart phone. VIDA will assign an individual professional health coach selected from a pool of well-trained and experienced health professionals-nutritionists, fitness trainers, nurses and health educators. Each coach will engage their patient in a productive and meaningful health mentorship on a daily basis. The coach and patient work as a team to successfully set goals and make small changes that add up to significant improvements in the patients' dietary choices, physical activity, medication management, as well as understanding of their health status. Physical Activity: A goal of "total number of steps" to attain daily will be provided by the Duke study team to the patient and monitored using a Fitbit activity tracker.

Behavioral: Mobile Health Application

Usual Care Group

NO INTERVENTION

Participants randomized to the usual care control arm will follow standard care as ordered by their individual, treating physician. Participants in the UC control arm will not receive any specific lifestyle recommendations from study personnel. They may, however, receive any lifestyle recommendations deemed appropriate by their usual clinical care providers. All participants will be contacted by study personnel in order to schedule visits at baseline and 12-weeks for the outcome assessments.

Interventions

Health coaching is an innovative, holistic approach oriented towards one's full health and wellbeing. Coaches provide mentoring and support regarding many areas of life that impact one's health with a focus on skill-building. Health coaches do not provide medical advice, treat any medical conditions, provide mental health therapy, or provide individualized assessments of nutrient needs. Health coaches will not conduct medication counseling activities that would alter the prescribed regimen nor provide medication information/advice that would be considered the practice of medicine or pharmacy. A Fitbit activity monitor will be used to track daily physical activity and provide real-time feedback to the participant.

Also known as: Health Coaches, Physical Activity Tracker
Mobile Health Application Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Graduates of CR, who were originally enrolled in CR following myocardial infarction (MI), percutaneous coronary intervention (PCI), or coronary artery bypass graft (CABG) or with stable angina
  • Adequate clinical stability has been achieved in the judgment of the investigator to allow participation in study assessments and the intervention
  • Ability to participate in a mobile health program with access to smartphones utilizing Apple and Android platforms
  • Signed informed consent document indicating that the patient understands the purpose of and procedures required for the study and is willing to participate in the study

You may not qualify if:

  • Acute symptoms of coronary artery disease
  • Decompensated heart failure
  • Severe valvular heart disease
  • Severe pulmonary hypertension
  • End stage renal disease
  • Heart failure, New York Heart Association (NYHA) class IV
  • Cardiac transplantation
  • Terminal illness with life expectancy \< 1 year
  • Impairment from stroke, injury or other medical disorder that precludes participation in the intervention
  • Dementia that precludes ability to participate in and follow study protocols
  • Enrollment in a clinical trial not approved for co-enrollment
  • Inability or unwillingness to comply with the study requirements

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Duke Medicine - Duke Molecular Physiology Institute

Durham, North Carolina, 27705, United States

Location

Related Publications (1)

  • Duscha BD, Piner LW, Patel MP, Craig KP, Brady M, McGarrah RW 3rd, Chen C, Kraus WE. Effects of a 12-week mHealth program on peak VO2 and physical activity patterns after completing cardiac rehabilitation: A randomized controlled trial. Am Heart J. 2018 May;199:105-114. doi: 10.1016/j.ahj.2018.02.001. Epub 2018 Feb 7.

MeSH Terms

Conditions

Coronary Artery DiseaseMotor Activity

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular DiseasesBehavior

Study Officials

  • William E Kraus, MD

    Duke University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2015

First Posted

May 1, 2015

Study Start

July 1, 2015

Primary Completion

March 20, 2017

Study Completion

March 20, 2017

Last Updated

February 5, 2018

Record last verified: 2018-01

Locations