A Comparison Between the Aysis® Cs2 (General Electrics) Ventilator in EtControl® Mode and the Perseus® A 500 (Dräger) in VaporView® Mode on Maniability and Consumption of Desflurane

NCT02427971 | Unknown

• 1 other identifier: 2014-A01476-41
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The Aysis® Cs2 ventilator offers an automated control of end-tidal inhalation anesthetic concentration, the EtControl® mode. A low Fresh Gas Flow (FGF) (0.5L/min) is kept during the maintenance of the anesthesia, decreasing the expensive consumption of halogenated agents. The Perseus® A 500 offers a VaporView® mode that gives the evolution of inspired (Fi) and end-tidal (Fe) fractions of halogenated agents for 20 minutes based on the delivered fraction (Fd). FGF remains adjusted manually by the practitioner. This mode also makes it possible to maintain a low FGF (0.5 L/min), provided the halogen Fd is set to maintain a steady Fe curve. The goal of this work was to compare the maniability of the intraoperative administered concentrations and the consumption of Desflurane between these 2 modalities of administration.

Conditions

Anesthetics Agent; Consumption; Inhalation; Desflurane

Outcome Measures

Primary Outcomes (1)

• Consumption of Desflurane between these 2 modalities of administration.

  Des consumption was measured by micrometric weighing of the vaporizer before and after general anesthesia and a milliliter per min consumption was calculated

  Time of general anesthesia (1h minimum up to 12h)

Secondary Outcomes (3)

• Comparison of inspired (Fi) and end-tidal (Fe) fractions of halogenated evolution

  Time of general anesthesia (1h minimum up to 12h)

• Anesthesia depth monitoring by BIS

  Time of general anesthesia (1h up to 12h)

• Hemodynamic stability

  Time of general anesthesia (1h minimum up to 12h)

Study Arms (2)

Perseus

Use of Perseus® A 500 with VaporView® mode that gives the evolution of inspired (Fi) and end-tidal (Fe) fractions of halogenated agents for 20 minutes based on the delivered fraction (Fd). FGF remains adjusted manually by the practitioner. This mode also makes it possible to maintain a low FGF (0.5 L/min)

Aysis

Use of Aysis® Cs2 ventilator with automated control of end-tidal inhalation anesthetic concentration, EtControl® mode.

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

ASA 1/2 adult patients undergoing a general anesthesia of more than one hour.

You may qualify if:

• patients undergoing a general anesthesia for intra abdominal surgery during more than one hour
• ASA 1or 2

You may not qualify if:

• contraindication to halogenated agent
• thoracic surgery
• no french speaking

Sponsors & Collaborators

• Saint Antoine University Hospital: lead

Study Sites (1)

Hôpital Saint-Antoine

Paris, France

RECRUITING

MeSH Terms

Conditions

Respiratory Aspiration

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: April 15, 2015
• First Posted: April 28, 2015
• Study Start: January 1, 2015
• Primary Completion: April 1, 2015
• Study Completion: April 1, 2015
• Last Updated: April 28, 2015

Record last verified: 2015-04

Locations

FR (1)