Weight Outlooks by Restriction of Diet and Sleep

NCT02413866 | Completed

• 1 other identifier: Pro00036519
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine whether chronic moderate sleep restriction effects the amount of body fat and lean mass loss, and calorie expenditure, in individuals who are participating in a dietary weight loss program.

Conditions

Weight

Keywords

body composition; anthropometry

Outcome Measures

Primary Outcomes (1)

• body composition measured via DXA scans

  Body composition will be measured via DXA scans prior to intervention and post intervention to compare losses in lean body mass and fat mass.

  4 months

Study Arms (2)

Calorie Restriction Only

EXPERIMENTAL

Participants in this group will be decreasing their caloric intake to approximately 95% of their resting metabolic rate. We will provide one meal for 4 days of the week, and participants will be required to keep an accurate dietary record of all food and drink. Participants assigned to this group will be instructed to keep a fixed sleep schedule based on their own sleep/napping habits.

Behavioral: Calorie restriction only

Sleep & Calorie Restriction

EXPERIMENTAL

Participants in this group will decrease their caloric intake to approximately 95% of their resting metabolic rate in addition to reducing their total time in bed by 90 minutes 5 days a week.

Behavioral: Sleep & calorie restriction

Interventions

Calorie restriction only BEHAVIORAL

Participants randomly assigned to this group will be instructed to reduce their daily energy intake to 95% of their resting metabolic rate.

Calorie Restriction Only

Sleep & calorie restriction BEHAVIORAL

Participants randomly assigned to this group will be instructed to reduce their total time in bed by 90 minutes 5 days a week, in addition to restricting their dietary intake to approximately 95% of their resting metabolic rate.

Sleep & Calorie Restriction

Eligibility Criteria

• Age: 35 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• age between 35-55 years,
• BMI between 30-35 kg/meters squared,
• total sleep time between 6.5-8 hours

You may not qualify if:

• work requiring changing schedule,
• use of sleep aids or sleep medication

Sponsors & Collaborators

• University of South Carolina: lead

Study Sites (1)

University of South Carolina

Columbia, South Carolina, 29208, United States

Location

Related Publications (2)

• Sparks JR, Porter RR, Youngstedt SD, Bowyer KP, Durstine JL, Wang X. Effects of moderate sleep restriction during 8-week calorie restriction on lipoprotein particles and glucose metabolism. Sleep Adv. 2021 Jan 28;1(1):zpab001. doi: 10.1093/sleepadvances/zpab001. eCollection 2020.

  PMID: 33644759 DERIVED

• Wang X, Sparks JR, Bowyer KP, Youngstedt SD. Influence of sleep restriction on weight loss outcomes associated with caloric restriction. Sleep. 2018 May 1;41(5):10.1093/sleep/zsy027. doi: 10.1093/sleep/zsy027.

  PMID: 29438540 DERIVED

MeSH Terms

Conditions

Body Weight

Interventions

Sleep

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nervous System Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Xuewen Wang, PhD

  University of South Carolina

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 7, 2015
• First Posted: April 10, 2015
• Study Start: January 1, 2015
• Primary Completion: November 1, 2016
• Study Completion: November 1, 2016
• Last Updated: April 19, 2019

Record last verified: 2016-12

Locations

US (1)