Telerehabilitation for Attention and Memory in Stroke

NCT02405351 | Completed

• 1 other identifier: TEAMS02102014
• Study Type: interventional
• Target: 7
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators propose to develop a Telerehabilitation approach to working memory training for patients experiencing working memory deficits post stroke. The investigators have currently developed a game-like computerized working memory training program that can be accessed via the internet for research purposes. The investigators propose to refine the website to focus more on clinically based training, and to evaluate the feasibility and initial effectiveness of this approach in a pilot study with participants after stroke.

Conditions

Stroke

Keywords

Telemedicine, Stroke, Working Memory, Cognitive Training

Outcome Measures

Primary Outcomes (2)

• Baseline working memory function

  Using operation and symmetry span task, as well as as Sternberg memory scanning tasks Operation span task: A dual-task in which participants complete mathematical reasoning (e.g. solving a mathematical equation) while using short-term verbal memory to remember words. Symmetry span task: A dual task in which participants discriminate about the symmetry of visual stimuli while using short-term spatial memory to remember the locations of stimuli. Sternberg memory scanning tasks: A task that involved remembering various number of cards as memory test

  Baseline

• Change in working memory function between baseline and 6 weeks post training onset

  6 weeks post training onset

Secondary Outcomes (13)

• Baseline cognitive function

  Baseline

• Baseline anxiety/depression

  Baseline

• Baseline premorbid intelligence quotient (IQ)

  Baseline

• Baseline aphasia assessment

  Baseline

• Change in aphasia assessment 6 weeks post training onset

  6 weeks post training onset

Other Outcomes (2)

• Assessment of feasibility and usability of approach

  6 weeks post training onset

• Assessment of functional activities

  6 weeks throughout study participation

Study Arms (1)

Training Group

EXPERIMENTAL

Participants will be 10 individuals post stroke, living in the community. The intervention, adaptive working memory training, is a dual n-back working memory task. This training will take place once for 30 minutes per day, 5 days a week for 6 weeks, with one week dedicated for familiarizing participants to the program in the very beginning (i.e., Week 1).

Behavioral: Adaptive Working Memory Training

Interventions

Adaptive Working Memory Training BEHAVIORAL

The working memory training task will consist of an online adaptive working memory program that will test and extend patients' working memory capacity. Adaptive refers to the increase in the number of items that the patient is required to remember.

Training Group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• at least 3 months post first stroke documented clinically or by imaging
• subjective concerns or objective assessment data regarding deficits in attention and working memory ability
• normal or corrected-to-normal vision
• have access to a computer at home

You may not qualify if:

• severe aphasia or dementia
• other neurological diagnosis such as epilepsy, multiple sclerosis, Parkinson's disease
• current diagnosis of a severe psychiatric disorder such as major depressive disorder or psychosis

Sponsors & Collaborators

• Nova Scotia Health Authority: lead
• Heart and Stroke Foundation of Canada: collaborator

Study Sites (1)

Dalhousie University

Halifax, Nova Scotia, Canada

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Sarah Dolan, BSc

  Dalhousie University

  STUDY DIRECTOR

• Gail A Eskes, PhD

  Dalhousie University

  PRINCIPAL INVESTIGATOR

• Stephen Phillips, MD

  Capital District Health Authority; Dalhousie University

  STUDY CHAIR

• Anita Mountain, MD

  Capital District Health Authority; Dalhousie University

  STUDY CHAIR

• Diane MacKenzie, PhD

  Capital District Health Authority; Dalhousie University

  STUDY CHAIR

• Mary Gorman, MD

  St. Martha's Regional Hospital; Dalhousie University

  STUDY CHAIR

• Peggy Green

  Nova Scotia Health Authority

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 17, 2014
• First Posted: April 1, 2015
• Study Start: April 1, 2015
• Primary Completion: October 30, 2019
• Study Completion: October 30, 2019
• Last Updated: June 15, 2023

Record last verified: 2018-02

Locations

CA (1)