Training Attention and Eye Movement in ASD
Wireless EEG System for Training Attention and Eye Movement in ASD
1 other identifier
interventional
30
1 country
1
Brief Summary
Current therapies for autism target social and language behaviors, but due to the high-level nature of these skills any improvement rarely extends beyond the targeted behavior. This project uses new technology to implement a novel concept for behavioral intervention to improve basic attention and eye movement skills in ASD. Because these basic skills form the foundation for good social communication, training these abilities has the potential to improve a broad spectrum of clinical symptoms, and in young children may affect the course of development.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Nov 2015
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 23, 2015
CompletedFirst Posted
Study publicly available on registry
March 31, 2015
CompletedStudy Start
First participant enrolled
November 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2018
CompletedResults Posted
Study results publicly available
December 4, 2019
CompletedDecember 4, 2019
December 1, 2019
2.8 years
March 23, 2015
August 8, 2019
December 3, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Spatial Attention Baseline
This behavioral task assesses the participant's baseline ability to rapidly and accurately shift visual attention to different spatial locations. This task also reveals whether a participant becomes overly-focused ('stuck') at specific locations.
Pre-intervention
Saccadic Eye Movements Baseline
This task uses an eyetracker to measure the baseline speed and accuracy of a participant's saccadic eye movements in response to various stimuli. Measure is accuracy of first saccade in the anti-saccade task.
Pre-intervention
Change in Spatial Attention at 8 Weeks
This behavioral task assesses the change in the participant's ability to rapidly and accurately shift visual attention to different spatial locations as a result of the intervention.
end of Week 8
Change in Saccadic Eye Movements at 8 Weeks
This task uses an eyetracker to measure the change in the speed and accuracy of a participant's saccadic eye movements in response to various stimuli as a result of the intervention. Measure is accuracy of first saccade in an anti-saccade task.
end of Week 8
Study Arms (2)
Eye Movement Game Control
EXPERIMENTALCognitive Training Eye Motor Training
Hand Movement Game Control
ACTIVE COMPARATORCognitive Training Hand Motor Training
Interventions
A collection of video games that rely on various aspects of visual behavior (i.e. sustained attention, vigilance, rapid discrimination, etc) for successful play.
Game play will be controlled by the player's eye movements (via an eye tracking device)
Game play will be controlled by the player's hand movements (via a joystick).
Eligibility Criteria
You may qualify if:
- Participant has a diagnosis of Autism Spectrum Disorder (on Diagnostic and Statistical Manual -IV, Autism Diagnostic Observation Schedule, Autism Diagnostic Interview-Revised)
- Participant has a nonverbal Intelligence Quotient (IQ) of 85 or greater and verbal IQ of 70 or greater
- Cooperative and able to follow instructions
- Normal hearing acuity
- Normal or corrected-to-normal vision
You may not qualify if:
- Major medical or neurological problems including seizures, diagnosed epileptiform EEG abnormalities, migraine, tuberous sclerosis, fragile X, static encephalopathies resulting from prior Central Nervous System insults, significant premature birth, and history of exposure to teratogens, metabolic abnormalities, and history of head trauma, cerebral palsy, stroke, meningitis, brain tumor or additional psychiatric diagnoses
- Participants currently participating in vision therapy will be excluded
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of California San Diego
La Jolla, California, 92093-0959, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Jeanne Townsend, PhD, Professor of Neurosciences
- Organization
- University of California, San Diego
Study Officials
- PRINCIPAL INVESTIGATOR
Jeanne Townsend, Ph.D.
University of California, San Diego
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Neurosciences
Study Record Dates
First Submitted
March 23, 2015
First Posted
March 31, 2015
Study Start
November 1, 2015
Primary Completion
August 31, 2018
Study Completion
August 31, 2018
Last Updated
December 4, 2019
Results First Posted
December 4, 2019
Record last verified: 2019-12
Data Sharing
- IPD Sharing
- Will share
- Time Frame
- Data are available to share now (August 8, 2019) and can remain available indefinitely or as long as the National Database for Autism Research is supported.
- Access Criteria
- Data are shared through the National Database for Autism Research. Access is by registration and meeting eligibility requirements established by the National Institutes of Health for data sharing.
De-identified IPD is being shared through National Institutes of Health (NIH) National Database for Autism Research (NDAR).