NCT02398916

Brief Summary

Loop electrosurgical excision procedure (LEEP) is the primary diagnostic and therapeutic procedure employed in women with high-grade intraepithelial neoplasia of the cervix. The procedure usually performed in the outpatient setting under local anesthesia. However, it could be associated with significant pain and anxiety. The aim of this study is to examine the effects of listening to music during the procedure in reducing pain and anxiety.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2015

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

February 27, 2015

Completed
27 days until next milestone

First Posted

Study publicly available on registry

March 26, 2015

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
Last Updated

August 30, 2016

Status Verified

August 1, 2016

Enrollment Period

1.5 years

First QC Date

February 27, 2015

Last Update Submit

August 29, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Procedure-related pain, as measured by Visual Analog Scale

    During the procedure

Secondary Outcomes (2)

  • Procedure-related anxiety, as measured by Visual Analog Scale

    During the procedure

  • Procedure-related satisfaction, as measured by Visual Analog Scale

    During the procedure

Study Arms (2)

Music

EXPERIMENTAL

* Listening to relaxing music for the entire period starting from waiting period in the surgical waiting area until the end of the LEEP procedure * Undergoing LEEP according to the usual protocol

Behavioral: Music listening

Control

NO INTERVENTION

\- Undergoing LEEP according to the usual protocol without listening to music

Interventions

Music listeningBEHAVIORAL
Music

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women with confirmed or suspected high-grade intraepithelial neoplasia of the cervix

You may not qualify if:

  • Allergy to local anesthetic agent (lidocaine)
  • Pregnancy
  • Previous major surgical procedures on cervix (conization, LEEP, laser therapy, cryotherapy) or uterus
  • Using cardiac pacemaker or history of cardiac arrhythmia
  • Neurological disorder affecting perception of pain
  • History of lower urinary tract cancer
  • Coagulation defects
  • History of drug dependence
  • Lower genital tract infection
  • Apparent invasive cancer of the cervix
  • Hearing difficulty

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of OB-GYN, Faculty of Medicine, Chiang Mai University

Chiang Mai, Chiang Mai, 50200, Thailand

Location

MeSH Terms

Conditions

Uterine Cervical Dysplasia

Condition Hierarchy (Ancestors)

Precancerous ConditionsNeoplasmsUterine Cervical DiseasesUterine DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Study Officials

  • Kittipat Charoenkwan, MD

    Faculty of Medicine, Chiang Mai University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 27, 2015

First Posted

March 26, 2015

Study Start

February 1, 2015

Primary Completion

August 1, 2016

Study Completion

August 1, 2016

Last Updated

August 30, 2016

Record last verified: 2016-08

Locations