NCT02397369

Brief Summary

Tobacco use is the single most preventable cause of premature adult death globally. It is one of the major causes of death and disease in India, accounting for nearly 0.9 million deaths every year. Bombay Electric Supply and Transport (BEST), one of the biggest public transport undertaking in Mumbai City, has imposed a ban on tobacco use in public transport buses and under Motor Vehicle Act has empowered the drivers and bus conductors to take suitable action against commuters found to be using tobacco. However in addition to commuters using tobacco in the BEST premises, large number of bus drivers and conductors are known to use tobacco on the job. There are various approaches to a tobacco cessation programme, like behavioural therapy, pharmacotherapy, providing self help material, telephone counseling, quit lines etc. Hence in terms of the workplace environment, understanding the factors leading to tobacco use maintenance and the effective approaches for cessation is of critical importance for formulating workplace tobacco prevention and cessation interventions that are applicable to transport work employee settings. The success of these methods needs to be comparatively evaluated among the different forms of tobacco users. Hence, the present study will be undertaken with the following objectives:

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
4,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2015

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

March 2, 2015

Completed
22 days until next milestone

First Posted

Study publicly available on registry

March 24, 2015

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2020

Completed
Last Updated

December 22, 2017

Status Verified

December 1, 2017

Enrollment Period

5 years

First QC Date

March 2, 2015

Last Update Submit

December 21, 2017

Conditions

Keywords

Education and evaluate post intervention KAP

Outcome Measures

Primary Outcomes (1)

  • Knowledge, Attitudes and Practices (KAP) regarding tobacco among BEST employees.

    To study the Knowledge, Attitudes and Practices (KAP) regarding tobacco among BEST employees in Mumbai

    60 months

Other Outcomes (3)

  • Compliance for availing the services at Preventive Oncology screening facilities and Tobacco cessation clinic at the Tata Memorial Hospital

    60 months

  • Rate of oral pre-cancers among BEST employees

    60 months

  • Rate of tobacco cessation after one year follow-up

    60 months

Study Arms (4)

Tobacco users: Self Help

EXPERIMENTAL

Self-help intervention is defined as any manual or programme to be used by individuals to assist a quit attempt not aided by counsellors or group support.They include written materials on the health effects of tobacco, audio-or video tape or computer programmes.

Other: Tobacco users: Self Help

Tobacco users:Telephonic counseling

EXPERIMENTAL

Telephone counseling is a way of providing individual counseling via telephone conversation or telephone hotlines. It can be proactive or reactive.

Behavioral: Tobacco users:Telephonic counseling

Tobacco users:Behavioural therapy Only

EXPERIMENTAL

Behavioural therapy includes multiple sessions of Focus Group Discussion (FGD) and individual tobacco cessation counseling sessions. The participants in this group will be given advice to quit tobacco via multisession formal cognitive-behavioural therapy as per the Tobacco Cessation Clinic (TCC) guidelines.

Behavioral: Tobacco users:Behavioural therapy Only

Tobacco users:Pharmacologic

EXPERIMENTAL

Pharmacotherapy in the form of Nicotine Replacement Therapy based on individual need assessment to relieve withdrawal symptoms in tobacco users when trying to quit.

Behavioral: Tobacco users:Behavioural therapy OnlyOther: Tobacco users:Pharmacologic

Interventions

This group will be given pictorial material and minimal written materials/ pamphlets describing health hazards of smokeless forms of tobacco and tips on tobacco cessation in general. The material will be interactively tailored to individual tobacco consumption characteristics and they will be followed up after 12 months.

Also known as: Self help
Tobacco users: Self Help

This group will be given proactive as well as reactive counseling. Medical social workers will proactively call all participants regularly and offer tobacco cessation counseling. In addition, they will call those participants who have planned their quit dates. Dedicated independent mobile numbers with 12 hours help lines will be made available to the participants to maximise the level of support. It will be scheduled in response to the needs to answer any type of help pertaining to quitting tobacco.

Also known as: Telephonic
Tobacco users:Telephonic counseling

1. Focus Group discussion: This tobacco cessation intervention session will involve thirty minutes of focus group discussion with group behavioral therapy in groups of 5-10 individuals for reinforcement of tobacco use prevention and cessation advice. Group discussion is intended to improve understanding by exploring, sharing and reflecting psychosocial, familial, environmental issues which attribute to the problem. 2. Individual tobacco cessation counseling sessions: Individual counseling is commonly used to help people who are trying to quit tobacco. The counseling adopting an interactive problem-solving approach will be done by trained Medical Social Workers providing face-to-face sessions for 10-15 minutes per participant.

Tobacco users:Behavioural therapy OnlyTobacco users:Pharmacologic

Pharmaco Therapy will consist of: Nicotine Chewing Gums: Dose: 2 mg/4 mg, 10-15 pieces per day with maximum dose of 24 pieces/day depending on cravings Total Duration: 12 weeks Duration of treatment: Higher dose for 4-6 weeks, with weaning till 2-3 months Side effects: Bad taste, Throat irritation, burning in mouth, nausea, vomiting, hiccups, increased heart beat etc Nicotine Transdermal patches: Dose: 7 mg/10 mg/14 mg/21 mg -for 24-hours use. Total Duration: 12 weeks Duration of treatment: Higher strength patch for 2 weeks and depending on cravings will be gradually decreased till 4 weeks Side effects: Skin irritation, dizziness, sleep problems, increased heart beat etc

Also known as: Drug
Tobacco users:Pharmacologic

Eligibility Criteria

Sexmale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • BEST employees in Mumbai

You may not qualify if:

  • BEST employees not willing to give consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tata Memorial Hospital, Parel

Mumbai, Maharashtra, 400012, India

RECRUITING

MeSH Terms

Conditions

Patient ComplianceTobacco Use Cessation

Interventions

Pharmaceutical Preparations

Condition Hierarchy (Ancestors)

Patient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Gauravi A Mishra, Assoc Prof

    Tata Memorial Hospital, Mumbai

    PRINCIPAL INVESTIGATOR
  • Sharmila A Pimple, Professor

    Tata Memorial Hospital, Mumbai

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gauravi A Mishra, Assoc Prof

CONTACT

Sharmila A Pimple, Professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor & Physician

Study Record Dates

First Submitted

March 2, 2015

First Posted

March 24, 2015

Study Start

March 1, 2015

Primary Completion

March 1, 2020

Study Completion

March 1, 2020

Last Updated

December 22, 2017

Record last verified: 2017-12

Locations