NCT02395211

Brief Summary

The aim of this study is to evaluate feasibility of a proprioceptive stimulation under visual feedback treatment protocol (using Gloreha® device) compared to usual physiotherapy treatment in sub-acute stroke patient with Complex regional pain syndrome.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 16, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 23, 2015

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2018

Completed
Last Updated

February 3, 2017

Status Verified

February 1, 2017

Enrollment Period

2.9 years

First QC Date

March 16, 2015

Last Update Submit

February 2, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual Analogue Scale

    Change measures (weeks: 0,4,16, 28)

Secondary Outcomes (5)

  • Neuropathic Pain Symptom Inventory

    Change measures (weeks: 0,4,16, 28)

  • McGill Pain Questionnaire

    Change measures (weeks: 0,4,16, 28)

  • Erasmus MC modification to the (revised) Nottingham Sensory Assessment - Italian version

    Change measures (weeks: 0,4,16, 28)

  • Fugl-Meyer Upper Extremity

    Change measures (weeks: 0,4,16, 28)

  • Pressure Pain Threshold

    Change measures (weeks: 0,4,16, 28)

Study Arms (2)

Usual Physiotherapy

ACTIVE COMPARATOR
Behavioral: Usual Physiotherapy

Gloreha device

EXPERIMENTAL
Device: Gloreha device

Interventions

Usual physiotherapy consist of active or passive mobilization, extensor digiti and carpi functional electric stimulation, occupational therapy and taping. The intervention will last 30 minute a day x 4 weeks

Usual Physiotherapy

Proprioceptive stimulation under visual feedback are provided by the Gloreha device. The intervention will last 30 minute a day x 4 weeks

Gloreha device

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \> 18 years and \< 85 years
  • diagnosis of stroke \< 6 months prior to study enrollment
  • diagnosis of Complex regional pain syndrome according to Budapest Criteria

You may not qualify if:

  • neurological or psychiatric pathology
  • severe cardio-pulmonary, renal, hepatic diseases
  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ferrara University Hospital

Ferrara, Ferrara, 44121, Italy

RECRUITING

MeSH Terms

Conditions

Complex Regional Pain Syndromes

Condition Hierarchy (Ancestors)

Autonomic Nervous System DiseasesNervous System DiseasesPeripheral Nervous System DiseasesNeuromuscular Diseases

Study Officials

  • Sofia Straudi, MD

    Ferrara Rehabilitation Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Marco Da Roit, PT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 16, 2015

First Posted

March 23, 2015

Study Start

January 1, 2015

Primary Completion

December 1, 2017

Study Completion

June 1, 2018

Last Updated

February 3, 2017

Record last verified: 2017-02

Locations