NCT02393235

Brief Summary

Factors affecting the success of the treatment of infertility can evaluate before and after embryo transfer in two stages. Most of the patients reach the embryo transfer stage. Unfortunately, the investigators are able to intervene very few of the factors that will affect the success of the post-transfer. All factors and treatments that affect the implantation is vital to identify. Basically, healthy vasculature is essential for a successful implantation. The investigators will try to understand relationship between vascular resistance and type of infertility. The investigators will examine whether the effect of the ovarian uterine and spiral artery resistance over infertility.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
217

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2015

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2015

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

March 9, 2015

Completed
10 days until next milestone

First Posted

Study publicly available on registry

March 19, 2015

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
Last Updated

July 7, 2015

Status Verified

July 1, 2015

Enrollment Period

2 months

First QC Date

March 9, 2015

Last Update Submit

July 2, 2015

Conditions

Infertility

Keywords

unexplained infertilitytubal infertilitypulsatility indexresistance indexfertile women

Outcome Measures

Primary Outcomes (3)

  • The primary outcome measure of this study is to evaluate the possible difference in ovarian artery impedance to blood flow ( RI and PI) among unexplained infertility, tubal infertility and fertile group.

    2-3 month

  • The primary outcome measure of this study is to evaluate the possible difference in uterine artery impedance to blood flow (RI and PI) among unexplained infertility, tubal infertility and fertile group.

    2-3 month

  • The primary outcome measure of this study is to evaluate the possible difference in spiral artery impedance to blood flow ( RI and PI) among unexplained infertility, tubal infertility and fertile group.

    2-3 month

Study Arms (3)

unexplained infertility(n:75)

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure with doppler ultrasonography in the mid-luteal phase. ( 21th day)

Other: doppler ultrasonography

tubal infertility(n:75)

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure with doppler ultrasonography in the mid-luteal phase. ( 21th day)

Other: doppler ultrasonography

fertile group(n:75)

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure with doppler ultrasonography in the mid-luteal phase. ( 21th day)

Other: doppler ultrasonography

Interventions

doppler ultrasonographyOTHER

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure

fertile group(n:75)tubal infertility(n:75)unexplained infertility(n:75)

Eligibility Criteria

Age22 Years - 37 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Women received infertility treatment

You may qualify if:

  • unsuccessful infertility treatment
  • normal prolactin levels
  • normal thyroid stimulation hormone levels
  • no ovarian or pelvic surgery history

You may not qualify if:

  • To have systemic diseases
  • receive medical treatments which may influence the clearance or excretion of gonadotropins and sex steroids

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Suleymaniye Birth And Women's Health Education And Research Hospital

Istanbul, 34020, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Infertility

Interventions

Ultrasonography, Doppler, Transcranial

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Intervention Hierarchy (Ancestors)

EchoencephalographyNeuroradiographyNeuroimagingDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisRadiographyUltrasonographyUltrasonography, DopplerDiagnostic Techniques, NeurologicalInvestigative Techniques

Study Officials

  • Ali G Zebitay, M.D.

    Suleymaniye Birth And Women's Health Education And Research Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 9, 2015

First Posted

March 19, 2015

Study Start

March 1, 2015

Primary Completion

May 1, 2015

Study Completion

June 1, 2015

Last Updated

July 7, 2015

Record last verified: 2015-07

Locations

TU(1)