Influence of Serum Vitamin D Levels on Embryo Morphokinetic Parameters
1 other identifier
observational
100
1 country
1
Brief Summary
The aim of this study is observing the relation between serum Vitamin D levels and morphokinesis of time lapse monitored Day 5 embryo in between 18 and 38 years age women undergoing controlled ovarian hyperstimulation (COH) because of unexplained or tubal factor infertility. Individuals will be divided into 2 groups according to serum vitamin D levels as normal or low , and the influence of those levels in morphokinetic parameters of embryos will be identified.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2015
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 9, 2015
CompletedFirst Posted
Study publicly available on registry
February 18, 2015
CompletedStudy Start
First participant enrolled
April 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2016
CompletedJanuary 28, 2016
January 1, 2016
1.2 years
February 9, 2015
January 27, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
time to 2 pronucleus (PN) membrane breakdown, first cleavage and 3, 4, 5, 6, 7, and 8 cells stages, morula and blastocyst stage (t2, t3, t4, t5, t6, t7, t8, t Morula (M), t Blastocyst (B) )
between 17 and 120 hours
Study Arms (2)
vitamin D levels < 20ng/ ml
Vitamin D levels \< 20ng/ ml
vitamin D levels>20ng/ ml
Vitamin D levels \>20ng/ ml
Eligibility Criteria
participants will be recruited among infertile women who is seeking for IVF treatment and fullfilling the inclusion criteria.
You may qualify if:
- years to 38 years age, 2 or less in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) attempt history, Unexplained or tubal factor infertility, Serum Follicle Stimulating Hormone (FSH) \< 10, Antral Follicule Count (AFC)\> 6-8
You may not qualify if:
- Male factor infertility, Presence of endometriosis or adenomyosis,Diminished ovarian reserve
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Bahceci Cliniclead
Study Sites (1)
Bahceci Fulya IVF Center
Istanbul, Fulya, 34800, Turkey (Türkiye)
Related Publications (1)
Dennis NA, Houghton LA, Jones GT, van Rij AM, Morgan K, McLennan IS. The level of serum anti-Mullerian hormone correlates with vitamin D status in men and women but not in boys. J Clin Endocrinol Metab. 2012 Jul;97(7):2450-5. doi: 10.1210/jc.2012-1213. Epub 2012 Apr 16.
PMID: 22508713BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
February 9, 2015
First Posted
February 18, 2015
Study Start
April 1, 2015
Primary Completion
June 1, 2016
Study Completion
July 1, 2016
Last Updated
January 28, 2016
Record last verified: 2016-01