Blood Flow Within Active Myofascial Trigger Points Following Massage
2 other identifiers
interventional
28
1 country
1
Brief Summary
The physiological response at the myofascial trigger point (MTrP) to massage is not known, yet would provide important objective evidence for a treatment effect and clarify the resolution process of a MTrP.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Mar 2015
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2015
CompletedFirst Submitted
Initial submission to the registry
March 2, 2015
CompletedFirst Posted
Study publicly available on registry
March 17, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2017
CompletedSeptember 1, 2017
August 1, 2017
1.8 years
March 2, 2015
August 30, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in Blood Flow as measured by microdialysis
1 hr pre intervention and 1 hr post intervention
Secondary Outcomes (3)
Change in Glucose as measured by microdialysis
1 hr pre intervention and 1 hr post intervention
Change in Lactate as measured by microdialysis
1 hr pre intervention and 1 hr post intervention
Change in Pyruvate as measured by microdialysis
1 hr pre intervention and 1 hr post intervention
Study Arms (2)
Trigger point treatment
EXPERIMENTALTrigger point release
Ultrasound
SHAM COMPARATORSham US at Trigger point
Interventions
Eligibility Criteria
You may qualify if:
- Chronic or episodic tension-type headache
- active MTrP in upper trapezius
- age 21-49
- BMI between 18.5-24.9
- either gender
- any race or ethnicity
You may not qualify if:
- No or latent MTrP in the upper trapezius
- migraine 4+/month
- cluster headache
- fibromyalgia
- neurological disease (e.g. Alzheimer's disease, Parkinson's disease, muscular dystrophy, multiple sclerosis)
- cardiovascular disease (e.g. prior heart attack or stroke)
- diabetes
- pregnancy
- a bleeding disorder (Self-report of hemophilia, known lack/deficiency of clotting factors, or presently °taking anti-coagulants (e.g. warfarin, Coumadin))
- narcotic use
- currently receiving massage
- prior trigger point injection or needling therapies
- allergy to lidocaine-type anesthetics such as lidocaine and prilocaine
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Colorado Hospital
Aurora, Colorado, 80045, United States
Related Publications (1)
Moraska AF, Hickner RC, Rzasa-Lynn R, Shah JP, Hebert JR, Kohrt WM. Increase in Lactate Without Change in Nutritive Blood Flow or Glucose at Active Trigger Points Following Massage: A Randomized Clinical Trial. Arch Phys Med Rehabil. 2018 Nov;99(11):2151-2159. doi: 10.1016/j.apmr.2018.06.030. Epub 2018 Aug 6.
PMID: 30092205DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Albert Moraska, PhD
University of Colorado, Denver
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 2, 2015
First Posted
March 17, 2015
Study Start
March 1, 2015
Primary Completion
December 1, 2016
Study Completion
January 1, 2017
Last Updated
September 1, 2017
Record last verified: 2017-08