Multicenter Registry Comparing Preoperative Imaging for Primary Hyperparathyroidism

NCT02381925 | Withdrawn

• 1 other identifier: Pro00061739
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The study aims are:

1. 1.To compare the diagnostic performance of parathyroid four-dimensional CT (4D-CT), scintigraphy, and ultrasound in patients who underwent parathyroid surgery for primary hyperparathyroidism.
2. 2.To compare 4D-CT, scintigraphy, and ultrasound for the ability to perform focused parathyroidectomy, and for rates of persistent hyperparathyroidism and complications from parathyroid surgery.

Conditions

Parathyroid Adenoma

Keywords

CT; Scintigraphy; Ultrasound

Outcome Measures

Primary Outcomes (1)

• diagnostic performance of imaging

  6 months

Secondary Outcomes (3)

• ability to perform focused parathyroidectomy

  6 months

• rates of persistent hyperparathyroidism after parathyroidectomy

  6 months

• parathyroidectomy surgical complications

  6 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The subjects will include all patients, aged 18 years or older, who underwent parathyroid surgery from July 2009 to July 2016.

You may qualify if:

• patients having parathyroid surgery for primary hyperparathyroidism from July 2009 to June 2016

You may not qualify if:

• age less than 18 years
• parathyroid carcinoma
• secondary or tertiary hyperparathyroidism

Sponsors & Collaborators

• Duke University: lead
• University of California, Los Angeles: collaborator
• University of Arkansas: collaborator

MeSH Terms

Conditions

Parathyroid Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Endocrine System Diseases; Parathyroid Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 3, 2015
• First Posted: March 6, 2015
• Primary Completion: June 1, 2016
• Study Completion: December 1, 2016
• Last Updated: September 21, 2015

Record last verified: 2015-09