NCT01084356

Brief Summary

The purpose of the study is to check if the new CZT system has an advantage in detection of small osseous processes, thyroid adenomas, parathyroid adenomas and detection of sentinel node, in comparison with the techniques in use. Participants: 100 subjects male and female that come to the institute of nuclear medicine for routine screening examinations. The CZT screening takes 10 minutes and does not require any extra intervention to the routine screening.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2010

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

March 9, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 10, 2010

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
Last Updated

March 10, 2010

Status Verified

March 1, 2010

Enrollment Period

1 year

First QC Date

March 9, 2010

Last Update Submit

March 9, 2010

Conditions

Parathyroid AdenomaThyroid Adenoma

Keywords

CZTsentinel nodeosseous processes

Study Arms (4)

hand

patients admitted for Tc MDP for evaluation of carpal/metacarpal and finger bone lesions

thyroid

patients admitted for Tc thyroid scan

parathyroid

patients investigated for parathyroid adenoma

sentinel node

patients who are due to sentinel node biopsy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

consequtive patiants admitted for the above scans and consented to be further investigated by the CZT system

You may qualify if:

  • age over 18

You may not qualify if:

  • pregnancy
  • patients unable to understand and sign an informed consent
  • age under 18

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center

Tel Aviv, Israel

Location

Related Publications (7)

  • Gambhir SS, Berman DS, Ziffer J, Nagler M, Sandler M, Patton J, Hutton B, Sharir T, Haim SB, Haim SB. A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera. J Nucl Med. 2009 Apr;50(4):635-43. doi: 10.2967/jnumed.108.060020.

    PMID: 19339672BACKGROUND

  • Hruska CB, Phillips SW, Whaley DH, Rhodes DJ, O'Connor MK. Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors. AJR Am J Roentgenol. 2008 Dec;191(6):1805-15. doi: 10.2214/AJR.07.3693.

    PMID: 19020253BACKGROUND

  • Mueller B, O'Connor MK, Blevis I, Rhodes DJ, Smith R, Collins DA, Phillips SW. Evaluation of a small cadmium zinc telluride detector for scintimammography. J Nucl Med. 2003 Apr;44(4):602-9.

    PMID: 12679406BACKGROUND

  • Ketchum LE. New equipment in nuclear medicine, part 1: solid-state detectors. J Nucl Med. 1998 Nov;39(11):15N, 35N-36N. No abstract available.

    PMID: 9829562BACKGROUND

  • Rhodes DJ, O'Connor MK, Phillips SW, Smith RL, Collins DA. Molecular breast imaging: a new technique using technetium Tc 99m scintimammography to detect small tumors of the breast. Mayo Clin Proc. 2005 Jan;80(1):24-30. doi: 10.1016/S0025-6196(11)62953-4.

    PMID: 15667025BACKGROUND

  • O'Connor MK, Phillips SW, Hruska CB, Rhodes DJ, Collins DA. Molecular breast imaging: advantages and limitations of a scintimammographic technique in patients with small breast tumors. Breast J. 2007 Jan-Feb;13(1):3-11. doi: 10.1111/j.1524-4741.2006.00356.x.

    PMID: 17214787BACKGROUND

  • Tsuchimochi M, Hayama K, Oda T, Togashi M, Sakahara H. Evaluation of the efficacy of a small CdTe gamma-camera for sentinel lymph node biopsy. J Nucl Med. 2008 Jun;49(6):956-62. doi: 10.2967/jnumed.108.050740. Epub 2008 May 15.

    PMID: 18483107BACKGROUND

MeSH Terms

Conditions

Parathyroid NeoplasmsThyroid Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsEndocrine System DiseasesParathyroid DiseasesThyroid Diseases

Study Officials

  • Einat Even Sapir, PhD, MD

    Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Einat Even Sapir, PhD,MD

CONTACT

972-3-6974444evensap@tasmc.health.gov.il

Ayelet Kurzband, BA

CONTACT

972-3-6974444ayeletk@tasmc.health.gov.il

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

March 9, 2010

First Posted

March 10, 2010

Study Start

March 1, 2010

Primary Completion

March 1, 2011

Last Updated

March 10, 2010

Record last verified: 2010-03

Locations

IL(1)