NCT02380989

Brief Summary

Sports-related soft tissue injuries, such as sprains, strains, and contusions, are a common painful condition. Current treatment includes oral nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of intolerable gastrointestinal side effects. Ancient Indian healing system, Ayurveda addresses the need of sports medicine up to certain extent. In practice, there are different treatment modalities for injuries, uses of drugs \& dietetics as well as practices of rehabilitation. Although, previous evidences support the efficacy of ayurveda practices with significant reduction in pain, joint tenderness, joint swelling, mobility restriction and early morning joint stiffness. But there is no treatment studies have been performed to evaluate the clinical outcome for specific sports injuries. This study assessed the efficacy and safety of ayurveda gel and patches applied to the painful injury site for the treatment of acute minor sports injury pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Sep 2014

Shorter than P25 for phase_2

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2014

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2014

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 1, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 5, 2015

Completed
Last Updated

March 5, 2015

Status Verified

March 1, 2015

Enrollment Period

2 months

First QC Date

March 1, 2015

Last Update Submit

March 4, 2015

Conditions

Keywords

AyurvedaAcute painSports Injury

Outcome Measures

Primary Outcomes (1)

  • Change in Pain intensity (VAS)

    baseline to 3, 7 and 14 days

Study Arms (2)

Ayurveda

EXPERIMENTAL
Device: Ayurveda

Placebo

PLACEBO COMPARATOR
Device: Placebo

Interventions

AyurvedaDEVICE

Ayurveda combinations in the form of gel and patches were applied on acute pain site.

Ayurveda
PlaceboDEVICE
Placebo

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • inversion ankle injury;
  • injury sustained during sporting activity

You may not qualify if:

  • other lower limb injury;
  • concurrent fracture with or without dislocation or with or without complete rupture;
  • surgery for ankle injury.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

NMP Medical Research Institute

Mahesāna, Gujarat, India

Location

Khatri educational trust

Satnāli, Haryana, India

Location

GyanSanjeevani

Jaipur, Rajasthan, India

Location

MeSH Terms

Conditions

Acute PainAthletic Injuries

Interventions

Medicine, Ayurvedic

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsWounds and Injuries

Intervention Hierarchy (Ancestors)

Medicine, TraditionalComplementary TherapiesTherapeutics

Study Officials

  • Archanaben Nachiket, MA

    NMP Medical Research Institute

    PRINCIPAL INVESTIGATOR
  • Neha Sharma, PhD

    NMP Medical Research Institute

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 1, 2015

First Posted

March 5, 2015

Study Start

September 1, 2014

Primary Completion

November 1, 2014

Study Completion

December 1, 2014

Last Updated

March 5, 2015

Record last verified: 2015-03

Locations