NCT02376439

Brief Summary

This research studies the energy balance behaviors (usual eating, physical activity, sedentary) and non-shared experiences of siblings discordant for weight (one sibling is lean the other is overweight).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
176

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2010

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2010

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2014

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

July 18, 2014

Completed
8 months until next milestone

First Posted

Study publicly available on registry

March 3, 2015

Completed
Last Updated

October 5, 2020

Status Verified

October 1, 2020

Enrollment Period

4 years

First QC Date

July 18, 2014

Last Update Submit

October 1, 2020

Conditions

Keywords

siblingsoverweightadolescent

Outcome Measures

Primary Outcomes (1)

  • Internal and external satiety calories consumed

    Calories consumed during ad libitum meals are measured after consumption of a high energy dense preload and a low energy dense preload and also after an external cue (smell) and a control condition.

    Calories consumed are measured at week 1, week 2, week 3 and week 4.

Study Arms (1)

Siblings

Siblings will consume four test meals after 4 different exposures, including two types of koolaid, a control and a smell condition.

Other: Kool-aid

Interventions

Participant drank two different types of kool-aid (sugar free and regular)

Siblings

Eligibility Criteria

Age13 Years - 17 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Forty-eight sibling pairs (24 pairs of boys and 24 pairs of girls, 96 total adolescents) age 13 to 17 years who are discordant for overweight/obesity will be studied to assess potentially modifiable non-shared experiences within and outside the family environment that alter energy balance behaviors and contribute to adolescent overweight. We will also measure the height and weight of up to 3 of their best friends.

You may qualify if:

  • between 13-17 years old
  • Have discordant same gender sibling (one is below 70th percentile, one is above 85th percentile
  • Speak/read English
  • Moderate or greater liking of study foods

You may not qualify if:

  • No current diagnosis of a psychiatric or eating disorder.
  • No dieting, dietary restrictions, or allergies that would interfere with study participation.
  • No medications or conditions that could influence taste or appetite.
  • No health concern or physical disability that would limit participation in physical activity.
  • No endocrine or central nervous system disorder that could produce overweight.
  • No current use of tobacco or nicotine products by the adolescent siblings.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University at Buffalo

Buffalo, New York, 14214, United States

Location

MeSH Terms

Conditions

ObesityOverweight

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Leonard Epstein, Ph.D.

    University at Buffalo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 18, 2014

First Posted

March 3, 2015

Study Start

April 1, 2010

Primary Completion

April 1, 2014

Study Completion

April 1, 2014

Last Updated

October 5, 2020

Record last verified: 2020-10

Locations