NCT02374177

Brief Summary

The purpose of this study is to prove the correlation between the post-operative delirium (POD) and anesthetic agents. The investigators hypothesized that intravenous anaesthetics would show the lower incidence of POD, compared with inhalation anaesthetics in off-pump CABG.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
292

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2014

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2014

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2015

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

February 4, 2015

Completed
23 days until next milestone

First Posted

Study publicly available on registry

February 27, 2015

Completed
Last Updated

February 27, 2015

Status Verified

February 1, 2015

Enrollment Period

1 month

First QC Date

February 4, 2015

Last Update Submit

February 23, 2015

Conditions

Delirium

Outcome Measures

Primary Outcomes (1)

  • Incidence of postoperative delirium

    up to postoperative 7 days

Study Arms (2)

Propofol group

Patient anesthetized using propofol

Sevoflurane group

Patients anesthetized using sevoflurane

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The medical records of the patients undergoing off-pump CABG in Konkuk University Medical Centre from Jan 2010 to Aug 2014 were retrospectively reviewed.

You may qualify if:

  • Patients undergoing off-pump coronary artery bypass grafting

You may not qualify if:

  • Other concurrent surgery
  • Conversion from off-pump coronary artery bypass grafting to on-pump coronary artery bypass grafting

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Koster S, Hensens AG, van der Palen J. The long-term cognitive and functional outcomes of postoperative delirium after cardiac surgery. Ann Thorac Surg. 2009 May;87(5):1469-74. doi: 10.1016/j.athoracsur.2009.02.080.

    PMID: 19379886BACKGROUND

MeSH Terms

Conditions

Delirium

Condition Hierarchy (Ancestors)

ConfusionNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurocognitive DisordersMental Disorders

Study Officials

  • Seong-Hyop Kim, Professor

    Konkuk University Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 4, 2015

First Posted

February 27, 2015

Study Start

November 1, 2014

Primary Completion

December 1, 2014

Study Completion

February 1, 2015

Last Updated

February 27, 2015

Record last verified: 2015-02