The Delirium-CS Canada Study
DELIRIUM-CS
Examining DELIRIUM in Postoperative Cardiac Surgery Patient in Canada: Providing a National "Snapshot" of an Increasingly Devastating Complication
1 other identifier
observational
235
1 country
12
Brief Summary
Delirium is a prevalent complication following cardiac surgery that is under-recognized using current methods of delirium detection and that may be better identified through a systematic and standardized perioperative screening protocol. The purpose of this study is to determine the incidence of postoperative delirium in the current era of cardiac surgery using a validated delirium-screening tool.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2014
Typical duration for all trials
12 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 30, 2014
CompletedFirst Posted
Study publicly available on registry
August 1, 2014
CompletedStudy Start
First participant enrolled
November 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2018
CompletedAugust 16, 2018
August 1, 2018
2.2 years
July 30, 2014
August 15, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Incidence of Delirium following Cardiac Surgery
Each center will be allowed to employ the delirium-screening tool currently in use at their institution provided that the tool is either the Intensive Care Delirium Screening Checklist (ICDSC) or Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). It is intended that either ICDSC or CAM-ICU, paired with a Richmond Agitation and Sedation Scale (RASS) or the Riker Sedation and Agitation Scale (SAS) be administered once per shift (i.e. with first assessment in the morning and a second assessment with the beginning of the evening shift). In addition, data regarding baseline demographic and clinical characteristics will be collected as well as data regarding the procedure performed (see Case Report Form (CRF). Patients will be considered as having had post-operative delirium if the results of at least one of the screening tests administered yielded a positive finding of delirium.
Delirium screening will be conducted for either up to 7 days following their date of surgery or up until their date of initial discharge from the intensive care unit, whichever comes first.
Eligibility Criteria
All patients undergoing cardiac surgery who are admitted to an ICU or CSRU following their procedure at twelve Canadian tertiary cardiac surgery centers in which patients are managed post-operatively in an intensive care unit (ICU) or cardiac surgery recovery unit (CSRU)
You may qualify if:
- All patients undergoing cardiac surgery who are admitted to an ICU or CSRU following their procedure
You may not qualify if:
- Patients in whom delirium cannot be reliably identified (e.g., previous debilitating stroke, cerebral palsy, severe dementia, severe hearing disabilities or inability to understand English or French, active seizure disorder or Child-Pugh class B or C cirrhosis)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- St. Boniface Hospitallead
- Foothills Medical Centrecollaborator
- Mazankowski Alberta Heart Institutecollaborator
- London Health Sciences Centrecollaborator
- Southlake Regional Health Centrecollaborator
- Toronto General Hospitalcollaborator
- Hamilton Health Sciences Corporationcollaborator
- Ottawa Heart Institute Research Corporationcollaborator
- Royal Victoria Hospital, Canadacollaborator
- Montreal Heart Institutecollaborator
- New Brunswick Heart Centrecollaborator
- Queen Elizabeth II Health Sciences Centrecollaborator
Study Sites (12)
Foothills Medical Centre
Calgary, Alberta, T2N 2T9, Canada
Mazankowski Alberta Heart Institute
Edmonton, Alberta, T6G 2B7, Canada
St. Boniface General Hospital
Winnipeg, Manitoba, R3C 4J8, Canada
New Brunswick Heart Centre
Saint John, New Brunswick, E2L 4L4, Canada
QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 2Y9, Canada
Hamilton General Hospital
Hamilton, Ontario, L8L2X2, Canada
London Health Sciences Centre
London, Ontario, N6A 5A5, Canada
Southlake Regional Health Centre
Newmarket, Ontario, L3Y 2P9, Canada
University of Ottawa Heart Institute
Ottawa, Ontario, K1Y 4W7, Canada
Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
Montreal Heart Institute
Montreal, Quebec, H1T 1C8, Canada
Royal Victoria Hospital
Montreal, Quebec, H3A 1A1, Canada
Related Publications (1)
DELIRIUM-CS Investigators*; Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group. Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study. CMAJ Open. 2017 Jul 13;5(3):E565-E569. doi: 10.9778/cmajo.20160136.
PMID: 28743102DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Rakesh C. Arora, MD, PhD, FRCSC
St. Boniface General Hospital - Cardiac Sciences
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
July 30, 2014
First Posted
August 1, 2014
Study Start
November 1, 2014
Primary Completion
January 1, 2017
Study Completion
July 1, 2018
Last Updated
August 16, 2018
Record last verified: 2018-08