NCT02368405

Brief Summary

This is a randomized controlled trial to study a nutrition education intervention in individuals with spinal cord injuries both in the acute rehabilitation setting (n = 100) and the community setting (n = 100). Participants in the treatment group will receive six interactive nutrition lectures based upon a successful program that has been used in older adults titled "Eat Smart, Stay Well". The goals of intervention are to improve whole-grain, fruit and vegetable, and low-fat dairy intake and reduce fat and saturated fat intake. Secondary outcomes will include improvements in waist circumference of body mass index and some biomarkers such as cholesterol and blood sugar.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
78

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2015

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

February 10, 2015

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 23, 2015

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 26, 2020

Completed
Last Updated

August 30, 2022

Status Verified

February 1, 2022

Enrollment Period

5.2 years

First QC Date

February 10, 2015

Last Update Submit

August 24, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Nutrition Behavior and Knowledge, measured by Likert scale

    Nutrition behavior will be recorded from two five point Likert scale questions ranging from 1 = not practicing the behavior to 5 = practicing it regularly. Questions are related to eating fruits and vegetables and to decreasing fat intake. The recorded scores for these questions will be pooled for nutrition behavior and range from 2 = very low to 10 = very high.

    Change from baseline at three months, and 12 months

Secondary Outcomes (6)

  • Body Mass Index

    Baseline and 12 months

  • Waist Circumference

    Baseline and 12 months

  • Laboratories - Fasting lipid panel

    Baseline and 12 months

  • Laboratories - Fasting blood glucose

    Baseline and 12 months

  • Laboratories - High Sensitivity C-reactive protein

    Baseline and 12 months

  • +1 more secondary outcomes

Study Arms (2)

Control

ACTIVE COMPARATOR

Control group will receive standard of care

Behavioral: Control

Treatment

EXPERIMENTAL

Participants in the treatment group will receive six interactive nutrition lectures over the course of three weeks. The treatment program is titled "Eat Smart, Live Better"

Behavioral: Eat Smart, Live Better

Interventions

ControlBEHAVIORAL

Participants in the control group will receive the standard nutrition lecture currently given at Carolinas Rehabilitation to all inpatients with spinal cord injuries. This one lecture is what is required by Commission on Accreditation for Rehabilitation Facilities (CARF)

Control

Intervention participants will participate in a series of six, 60-minute small group sessions of interactive nutrition education discussions led by a Registered Dietitian delivered over 3 weeks. They will also have one follow-up comprehensive nutrition education session approximately 3 months after receipt of the Eat Smart, Live Better curriculum. In order to help us assess the effectiveness of the nutrition education program, we will assess nutrition behavior and knowledge at this time as well. Community participants in the treatment group will attend the sessions at Carolinas Rehabilitation (CR). The control participants from the community will come to CR for the one standard nutrition lecture. Caregivers and spouses of all of the participants will be encouraged to attend the sessions.

Treatment

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • American Spinal Injury Association classification A, B, C as long as they are not functional ambulators

You may not qualify if:

  • Stage III or IV pressure ulcers, pregnancy, end-stage renal disease, treatment for cancer except for nonmelanoma skin cancer within the past five years, and chronic, nontobacco substance-abuse, cognitive impairment with inability to learn

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Carolinas Rehabilitation

Charlotte, North Carolina, 28203, United States

Location

Related Publications (2)

  • Hooper L, Abdelhamid AS, Jimoh OF, Bunn D, Skeaff CM. Effects of total fat intake on body fatness in adults. Cochrane Database Syst Rev. 2020 Jun 1;6(6):CD013636. doi: 10.1002/14651858.CD013636.

  • Lieberman JA, McClelland JW, Goff DC Jr, Racine E, Dulin MF, Bauman WA, Niemeier J, Hirsch MA, Norton HJ, Moore CG. Nutrition education for cardiovascular disease prevention in individuals with spinal cord injuries: study protocol for a randomized controlled trial. Trials. 2017 Dec 4;18(1):584. doi: 10.1186/s13063-017-2263-2.

MeSH Terms

Conditions

Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Spinal Cord DiseasesCentral Nervous System DiseasesNervous System DiseasesTrauma, Nervous SystemWounds and Injuries

Study Officials

  • Jesse A Lieberman, MD, MSPH

    Carolinas Rehabilitation

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Study allocation was placed in concealed envelopes by research volunteer who was not otherwise involved in the study.
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2015

First Posted

February 23, 2015

Study Start

February 1, 2015

Primary Completion

April 1, 2020

Study Completion

June 26, 2020

Last Updated

August 30, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations