NCT02368366

Brief Summary

Traumatic brain injury (TBI) is the most common cause of acquired disability in youth and a source of significant morbidity and family burden. Novel behavior problems are among the most common and problematic consequences, yet many youth fail to receive needed psychological services due to lack of identification and access. Linking youth with TBI to effective treatments could improve functional outcomes, reduce family burden, and increase treatment satisfaction. The investigators overarching aim is to compare the effectiveness, feasibility, and acceptability of three formats of family problem solving therapy (F-PST) for improving functional outcomes of complicated mild to severe adolescent TBI: therapist-guided, face-to-face; therapist-guided online; and self-guided, online F-PST.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
151

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2014

Typical duration for not_applicable

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 27, 2014

Completed
5 days until next milestone

Study Start

First participant enrolled

November 1, 2014

Completed
4 months until next milestone

First Posted

Study publicly available on registry

February 23, 2015

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2017

Completed
Last Updated

January 29, 2018

Status Verified

January 1, 2018

Enrollment Period

3 years

First QC Date

October 27, 2014

Last Update Submit

January 25, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Behavior Rating Inventory of Executive Function (BRIEF)

    Baseline, post-intervention and 3 months post-intervention

Secondary Outcomes (6)

  • Center for Epidemiology Scale for Depression (CES-D)

    Baseline, post-intervention and 3 months post-intervention

  • Health and Behavior Inventory (HBI)

    Baseline, post-intervention and 3 months post-intervention

  • Ohio State University (OSU) Traumatic Brain Injury (TBI) Identification Method (OSU TBI-ID)

    Baseline

  • Brief Symptom Inventory (BSI)

    Baseline, post-intervention and 3 months post-intervention

  • Strengths and Difficulties Questionnaire (SDQ)

    Baseline, post-intervention and 3 months post-intervention

  • +1 more secondary outcomes

Study Arms (3)

Therapist Guided Face to Face FPST

EXPERIMENTAL

Therapist Guided Face to Face Family Problem Solving Families assigned to this arm will meet with the therapist in person at the medical center TBI clinic. Sessions will last approximately 60 minutes and cover didactic content using printed handouts provided as part of a family workbook.

Behavioral: Therapist Guided Face to Face Family Problem Solving

Therapist Guided Online FPST

EXPERIMENTAL

Therapist Guided Online Family Problem Solving Families assigned to this arm will receive a password enabling them to access the online intervention materials throughout the course of the intervention. Each session of online F-PST consists of a self-guided online portion providing didactic content regarding the desired skill (i.e., problem-solving), video clips showing individuals and families modeling the skill, and exercises and assignments giving the family an opportunity to practice the skill. During synchronous, videoconference sessions with the therapist, the family will review the online materials and practice the problem-solving process.

Behavioral: Therapist Guided Online Family Problem Solving

Self-Guided Online FPST

EXPERIMENTAL

Self-Guided Online Family Problem Solving Families in the self-guided, online F-PST arm will receive a password enabling them to access the online intervention materials throughout the course of the intervention. They will receive access to the same web-modules as the therapist-guided group, but will review them on their own without therapist support. Participants in this group will be encouraged to complete web modules at the same schedule as participants in the other groups. If the family fails to log on or complete web modules, they will receive reminders via phone, text, or e-mail.

Behavioral: Self-Guided Online Family Problem Solving

Interventions

Families assigned to this arm will meet with the therapist in person at the medical center TBI clinic. Sessions will last approximately 60 minutes and cover didactic content using printed handouts provided as part of a family workbook.

Therapist Guided Face to Face FPST

Families assigned to this arm will receive a password enabling them to access the online intervention materials throughout the course of the intervention. Each session of online F-PST consists of a self-guided online portion providing didactic content regarding the desired skill (i.e., problem-solving), video clips showing individuals and families modeling the skill, and exercises and assignments giving the family an opportunity to practice the skill. During synchronous, videoconference sessions with the therapist, the family will review the online materials and practice the problem-solving process.

Therapist Guided Online FPST

Families in the self-guided, online F-PST arm will receive a password enabling them to access the online intervention materials throughout the course of the intervention. They will receive access to the same web-modules as the therapist-guided group, but will review them on their own without therapist support. Participants in this group will be encouraged to complete web modules at the same schedule as participants in the other groups. If the family fails to log on or complete web modules, they will receive reminders via phone, text, or e-mail.

Self-Guided Online FPST

Eligibility Criteria

Age14 Years - 19 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Moderate to severe TBI
  • Overnight hospital stay
  • English-speaking
  • Parent must be willing to provide informed consent

You may not qualify if:

  • Child does not live with parents or guardian
  • Child or parent has history of hospitalization for psychiatric problem
  • Child suffered a non-blunt injury (e.g., projectile wound, stroke, drowning, or other form of asphyxiation)
  • Diagnosed with moderate or severe mental retardation, autism, or a significant developmental disability

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

The Children's Hospital

Denver, Colorado, 80045, United States

Location

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States

Location

Case Western Reserve University

Cleveland, Ohio, 44106, United States

Location

MetroHealth Medical Center

Cleveland, Ohio, 44106, United States

Location

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

Related Publications (1)

  • Wade SL, Cassedy AE, Taylor HG, McNally KA, Kirkwood MW, Stancin T, Horn PS, Kurowski BG. Adolescent quality of life following family problem-solving treatment for brain injury. J Consult Clin Psychol. 2019 Nov;87(11):1043-1055. doi: 10.1037/ccp0000440. Epub 2019 Sep 26.

MeSH Terms

Conditions

Brain Injuries, TraumaticBrain EdemaCraniocerebral TraumaBrain Hemorrhage, TraumaticHematoma, SubduralBrain ConcussionHead Injuries, ClosedHematoma, Epidural, SpinalBrain ContusionWounds and InjuriesDisorders of Environmental OriginTrauma, Nervous SystemBrain Injuries

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesIntracranial Hemorrhage, TraumaticIntracranial HemorrhagesCerebrovascular DisordersVascular DiseasesCardiovascular DiseasesHematomaHemorrhagePathologic ProcessesPathological Conditions, Signs and SymptomsWounds, NonpenetratingContusions

Study Officials

  • Shari Wade, PhD

    Children's Hospital Medical Center, Cincinnati

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 27, 2014

First Posted

February 23, 2015

Study Start

November 1, 2014

Primary Completion

November 1, 2017

Study Completion

November 1, 2017

Last Updated

January 29, 2018

Record last verified: 2018-01

Locations