NCT02362698

Brief Summary

this research adopted multicentered, randomly and parallel control methods to observe the clinical effects of electro-acupuncture combined psychological intervention on internet addiction disorder, aim to provide a convenient, affordable and effective clinical protocol.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2010

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2011

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2012

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

January 3, 2015

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 13, 2015

Completed
Last Updated

February 13, 2015

Status Verified

February 1, 2015

Enrollment Period

1.7 years

First QC Date

January 3, 2015

Last Update Submit

February 12, 2015

Conditions

Addiction

Outcome Measures

Primary Outcomes (3)

  • the change of the level of brain N-acetylaspartate on magnetic resonance spectroscopy from baseline at 40 days

    analysis

    day 1 and the day after treatment(treatment covered 40 days) had completed

  • the change from baseline of the total scores on Internet Addiction Test(IAT) at 40 days

    questionnaire

    day 1 and the day after treatment(treatment covered 40 days) had completed

  • the change of the level of brain choline on magnetic resonance spectroscopy from baseline at 40 days

    analysis

    day 1 and the day after treatment(treatment covered 40 days) had completed

Study Arms (2)

electro-acupuncture

EXPERIMENTAL

Receiving electro-acupuncture treatment once every other day, half an hour per treatment, 10 times as one treatment course, subjects received 2 courses of treatment.

Other: electro-acupuncture

psychological intervention

ACTIVE COMPARATOR

Receiving cognitive behavioral therapy once every four days, each time two hours. Five times intervention as one treatment course, subjects received 2 courses of treatment.

Other: psychological intervention

Interventions

electro-acupunctureOTHER

13points were selected including he-gu(LI4), nei-guan(PC6), tai-chong(LR3) and san-yin-jiao(SP6) from both sides, bai-hui(GV20) and si-shen-cong(EX-HN1) from head. HANS-200A acupoints stimulator, which had two output channels, was connected to some selected points. Dilatational wave was adopted in this research, the frequency of rarefaction wave was 2 hertz and condensation wave was 100 hertz, with a waviness width of 0.3ms. Switched the stimulator on after connected the poles to the needles, adjusted the intensity of output gradually from 0 milliampere to the extent of subject's maximum tolerance. Then needles would be remained on the body for half an hour.

electro-acupuncture
psychological interventionOTHER

Cognitive behavioral therapy was adopted by national accredited professional psychologist, in the form of team work and individual counseling, aim to help IA participants to understand their deviant behaviors, correct unhealthy cognitive states and eventually retrieve normal life style.

psychological intervention

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Subjects manifested three or more among the seven following conditions within one year could be defined as internet addiction:
  • (1) Tolerance, complied with either one: ①Satisfaction obtaining through markedly increasing time online ②Spending same period of time online but with dramatic declining satisfaction.
  • (2) Any following symptoms appeared after quitting internet surfing: ①Obvious withdrawal syndrome: A-- Quitted or decreased long time internet surfing. B--Within one month after A, two or more following symptoms appeared: (a) Depressed. (b) Psychomotor fidgety. (c) Compulsively thought things happened online. (d) Hallucinated or dreamed about internet related stuff. (e) Consciously or unconsciously carried out tapping the keyboard movement. C--The symptoms in B led to unexpected damage to one's social life, work and other important aspects of life, even depression. ②Desperate to surf the internet or seek similar online service in a bid to relieve or avoid withdrawal syndrome.
  • (3) More frequent online behaviors or longer online time than planned.
  • (4) Had been trying hard to reduce or control internet use but never succeeded.
  • (5) Spent large amount of time on internet related things, such as purchasing online books, trying out new browsers, organizing downloaded files, etc.
  • (6) Giving up or reducing important social, work or entertainment activities.
  • (7) Despite unfavorable physical, mental, social or work consequences, continued to use internet.

You may not qualify if:

  • Other psychiatric disease history.
  • Drug addiction history
  • Severe cardiovascular disease, blood diseases, malignant tumors or any other contraindication of electro-acupuncture.
  • Allergic to acupuncture treatment.
  • Participants with intracranial diseases or abnormal scalp structure.
  • Participants with metal implant.
  • Color blindness, left handedness.
  • Women in gestation or lactation period.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Peng W, Wang Y, Hao Q, Wang J, Chen Y, Qiu M, Tu Y, Li H, Zhu T. Effects of Electroacupuncture Combined With Psychological Intervention on Depressive Status and Contingent Negative Variation in Patients With Internet Addiction Disorder: A Randomized Controlled Trial. Front Psychiatry. 2021 Nov 15;12:722422. doi: 10.3389/fpsyt.2021.722422. eCollection 2021.

    PMID: 34867514DERIVED

MeSH Terms

Conditions

Behavior, Addictive

Interventions

Psychosocial Intervention

Condition Hierarchy (Ancestors)

Compulsive BehaviorImpulsive BehaviorBehavior

Intervention Hierarchy (Ancestors)

PsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Tianmin Zhu, Doctor

    Chengdu University of Traditional Chinese Medicine

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 3, 2015

First Posted

February 13, 2015

Study Start

January 1, 2010

Primary Completion

October 1, 2011

Study Completion

October 1, 2012

Last Updated

February 13, 2015

Record last verified: 2015-02