NCT02362477

Brief Summary

The immediate objective of this project is to evaluate the clinical effectiveness of a telemental health modality (video-teleconferencing) for providing an evidence-based group intervention to female rural veterans, Reservists, National Guardsmen, and civilians suffering with PTSD. This study is an expansion, seeking to add a treatment arm of women, to an already CDMRP-funded study that completed in July 2014 treating male combat veterans with military-related PTSD. The long-term objective of this project is to disseminate an empirically sound TMH PTSD protocol for male and female veterans, Reserve and Guard that will extend the use of CPT to remote rural sites. It is hypothesized that using VTC, will be as effective as the in-person mode of service delivery for providing CPT.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
126

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started Sep 2010

Typical duration for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2010

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 4, 2015

Completed
9 days until next milestone

First Posted

Study publicly available on registry

February 13, 2015

Completed
Last Updated

February 13, 2015

Status Verified

February 1, 2015

Enrollment Period

4.3 years

First QC Date

February 4, 2015

Last Update Submit

February 9, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Clinician Administered PTSD Scale (CAPS-IV)

    6 months post-treatment

Study Arms (2)

Control CPT

ACTIVE COMPARATOR

'Cognitive Processing Therapy in-person. Cognitive Processing Therapy is delivered to female veterans and civilians, who have been diagnosed with PTSD, in-person.

Behavioral: Cognitive Processing Therapy in-person

Experimental CPT via VTC

EXPERIMENTAL

'Cognitive Processing Therapy through videoteleconference. Cognitive Processing Therapy is delivered to female veterans and civilians, who have been diagnosed with PTSD, through videoteleconference.

Behavioral: Cognitive Processing Therapy through videoteleconference

Interventions

Cognitive Processing Therapy is delivered to female veterans and civilians, who have been diagnosed with PTSD, in-person.

Also known as: CPT-NP
Control CPT

Cognitive Processing Therapy is delivered to female veterans and civilians, who have been diagnosed with PTSD, through videoteleconference.

Also known as: CPT-VTC
Experimental CPT via VTC

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • diagnosis of current PTSD established by the Clinician-Administered PTSD Scale (CAPS) and
  • a stable psychotropic medication regimen for a minimum of 45 days prior to study entry for those taking such medications.

You may not qualify if:

  • significant cognitive impairment or history of organic mental disorder,
  • active psychotic symptoms/disorder,
  • active homicidal or suicidal ideation,
  • current substance dependence, and
  • unwillingness to refrain from substance abuse during treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Pacific Islands Healthcare System

Honolulu, Hawaii, 96819, United States

Location

Related Publications (1)

  • Glassman LH, Mackintosh MA, Wells SY, Wickramasinghe I, Walter KH, Morland LA. Predictors of Quality of Life Following Cognitive Processing Therapy Among Women and Men With Post-Traumatic Stress Disorder. Mil Med. 2020 Jun 8;185(5-6):e579-e585. doi: 10.1093/milmed/usz474.

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Officials

  • Leslie A. Morland, Psy.D.

    VA Pacific Islands Healthcare System

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 4, 2015

First Posted

February 13, 2015

Study Start

September 1, 2010

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

February 13, 2015

Record last verified: 2015-02

Locations