Evaluation of Myocardial Viability : Dual Energy Cardiac CT vs. Cardiac MRI

NCT02360150 | Terminated

• 1 other identifier: 2013/205/HP
• Study Type: interventional
• Target: 31
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is therefore to show that associated with cardiac angiography echocardiography, in myocardial seen late, would provide the information necessary for the decision revascularization, in a timely manner. This would allow the patient to avoid duplication of tests including risk related to coronary angiography (bleeding complications, stroke ...) and those related to the implantation of coronary stent (stent) without expected earnings in case of non-viability . This would also reduce the length of hospital stay and costs due to numerous reviews.

Conditions

Myocardial Infarction

Keywords

cardiac angiography; cardiac MRI

Outcome Measures

Primary Outcomes (1)

• Number of patient with a possible evaluation of myocardial viability using dual-energy cardiac CT

  To study the sensitivity of dual-energy cardiac CT for the evaluation of myocardial viability, in patients with late presentation myocardial infarction.

  Day 4

Secondary Outcomes (1)

• Number of patient with a possible evaluation of myocardial viability using cardiac MRI

  Day 4

Study Arms (1)

second propeller arm scanner

EXPERIMENTAL

The experimental procedure is to conduct a second helical scanner strictly centered on the heart, 10 minutes after the first helix without inject contrast medium, to assess late enhancement to the inclusion visit.

Radiation: second propeller arm scanner

Interventions

second propeller arm scanner RADIATION

The experimental procedure is to conduct a second helical scanner strictly centered on the heart, 10 minutes after the first helix without inject contrast medium, to assess late enhancement.

second propeller arm scanner

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Man or woman
• Major patient
• Patient with electrical, biological and clinical signs of myocardial infarction, with late presentation (\>24 hours)
• Creatinine clearance (calculated using the Cockcroft (\<age 65) or MDRD (\> 65 years))formula \> 30 ml / min.
• Affiliation to the french social security scheme.
• Women of childbearing age: Negative pregnancy test (urine test).
• Postmenopausal women, menopause confirmation of diagnosis
• Patient able to understand the spoken and written French.
• Signature of informed consent

You may not qualify if:

• Collapsus or organ failure requiring urgent care in intensive care unit
• Arrhythmia and/or non-reducible tachycardia.
• History of allergic reaction after iodinated contrast medium injection.
• History of nephrogenic systemic fibrosis.
• History of claustrophobia
• Unbalanced asthma.
• Acute pulmonary edema.
• Pregnant or breastfeeding women.
• Clinical signs of thyrotoxicosis.
• Person placed under judicial protection,
• Patient suffering from serious psychiatric disease.
• Patients participating in another clinical trial.
• Contraindication to MRI

Sponsors & Collaborators

• University Hospital, Rouen: lead

Study Sites (1)

University Hospital of Rouen

Rouen, Normandy, 76031, France

Location

MeSH Terms

Conditions

Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Officials

• Benjamin DUBOURG, Doctor

  University Hospital, Rouen

  PRINCIPAL INVESTIGATOR

• Jean-Nicolas DACHER, Professor

  University Hospital, Rouen

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 15, 2014
• First Posted: February 10, 2015
• Study Start: January 10, 2015
• Primary Completion: October 7, 2016
• Study Completion: October 7, 2016
• Last Updated: April 14, 2026

Record last verified: 2026-04

Locations

FR (1)