NCT07465692

Brief Summary

Endovascular intervention is one of the most effective treatment for acute coronary syndrome. Therefore, studying the impact of various medical rehabilitation programs on the course of coronary heart disease, patient quality of life, restenosis, and prognosis is of scientific and practical interest. Medical rehabilitation is a crucial stage in patient care after myocardial revascularization. Regular moderate-intensity physical activity helps improve endothelial function and has anti-inflammatory and antithrombogenic effects. Improving a patient's prognosis after myocardial infarction depends on the duration and intensity of cardiac rehabilitation programs, as well as the patient's motivation. Therefore, this issue requires further study, particularly in patients who have undergone endovascular interventions on coronary arteries.

Trial Health

83
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,046

participants targeted

Target at P75+ for not_applicable

Timeline
6mo left

Started Jun 2013

Longer than P75 for not_applicable

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress96%
Jun 2013Dec 2026

Study Start

First participant enrolled

June 1, 2013

Completed
12.8 years until next milestone

First Submitted

Initial submission to the registry

March 6, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 12, 2026

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

March 12, 2026

Status Verified

March 1, 2026

Enrollment Period

13.5 years

First QC Date

March 6, 2026

Last Update Submit

March 6, 2026

Conditions

Keywords

myocardial infarctionrehabilitationcoronary artery stenting

Outcome Measures

Primary Outcomes (1)

  • Combined

    Cardiovascular mortality, non-fatal acute myocardial infarction, non-fatal stroke, need for revascularization

    20 years

Secondary Outcomes (7)

  • All-cause mortality

    20 years

  • Composite endpoint of major adverse cardiovascular events (MACE)

    20 years

  • cardiovascular mortality

    20 years

  • myocardial infarction

    20 years

  • stroke

    20 years

  • +2 more secondary outcomes

Study Arms (2)

Physical training

EXPERIMENTAL

Integrated Rehabilitation consisting of exercise training and school for patients

Other: Physical training program

Control

NO INTERVENTION

Standard follow-up and attending school for patients at the participating heart center

Interventions

Integrated Rehabilitation consisting of exercise training for at least 1.5 months

Physical training

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Acute myocardial infarction, coronary artery stenting

You may not qualify if:

  • Age (younger 18 years, older 75 years)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 6, 2026

First Posted

March 12, 2026

Study Start

June 1, 2013

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

March 12, 2026

Record last verified: 2026-03