NCT02350075

Brief Summary

The aim of this study is to determine the clinical success of short implants (6mm) alone and standard implants (10mm) combined with sinus floor elevation in atrophic maxilla.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
225

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 19, 2015

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 29, 2015

Completed
1 month until next milestone

Study Start

First participant enrolled

March 1, 2015

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2017

Completed
Last Updated

May 16, 2019

Status Verified

May 1, 2019

Enrollment Period

2 years

First QC Date

January 19, 2015

Last Update Submit

May 14, 2019

Conditions

Keywords

short implantssinus floor elevationrandomized controlled trial

Outcome Measures

Primary Outcomes (1)

  • Implants survival rate

    Survival rate is defined by percentage of dental implants that remained in situ with or without modifications.

    1 year after implant placement

Secondary Outcomes (3)

  • Marginal bone loss

    1 year after implant placement

  • Complication rate

    1 year after implant placement

  • Patient-reported outcome (100-mm visual analogue scale (VAS)

    10 minutes after implant surgery

Study Arms (2)

Short implants group

EXPERIMENTAL

Patients receive short dental implants installation (6mm) without additional augmentation procedures.

Procedure: Dental implants installation

Standard implants with OSFE group

OTHER

Patients receive standard dental implants installation (10mm) combined with osteotome sinus floor elevation.

Procedure: Dental implants installationDevice: Osteotome Sinus floor elevation

Interventions

Dental implants installation is a procedure to insert dental implants into alveolar bone.

Short implants groupStandard implants with OSFE group

Osteotomes with different diameters are specially-designed device to vertically increase the bone volume in atrophic maxilla.

Standard implants with OSFE group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age≧18 years, partial edentulism in posterior maxilla for at least three months from tooth loss,
  • residual bone height range from 6-8mm,
  • sufficient bone width in edentulous region.

You may not qualify if:

  • The patients will be excluded on the basis of:
  • heavy smoker (\>10 cigarettes per days),
  • uncontrolled diabetes mellitus or other systemic diseases,
  • uncontrolled periodontal infection,
  • insufficient bone quality to achieve implant stability and
  • previous implant installation or bone grafting at surgical site.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jun-Yu Shi

Shanghai, Shanghai Municipality, 200011, China

Location

Related Publications (7)

  • Mangano FG, Shibli JA, Sammons RL, Iaculli F, Piattelli A, Mangano C. Short (8-mm) locking-taper implants supporting single crowns in posterior region: a prospective clinical study with 1-to 10-years of follow-up. Clin Oral Implants Res. 2014 Aug;25(8):933-40. doi: 10.1111/clr.12181. Epub 2013 Apr 28.

    PMID: 23621393BACKGROUND
  • Lai HC, Si MS, Zhuang LF, Shen H, Liu YL, Wismeijer D. Long-term outcomes of short dental implants supporting single crowns in posterior region: a clinical retrospective study of 5-10 years. Clin Oral Implants Res. 2013 Feb;24(2):230-7. doi: 10.1111/j.1600-0501.2012.02452.x. Epub 2012 Apr 2.

    PMID: 22469075BACKGROUND
  • Tan WC, Lang NP, Zwahlen M, Pjetursson BE. A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. Part II: transalveolar technique. J Clin Periodontol. 2008 Sep;35(8 Suppl):241-54. doi: 10.1111/j.1600-051X.2008.01273.x.

    PMID: 18724853BACKGROUND
  • Pjetursson BE, Tan WC, Zwahlen M, Lang NP. A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation. J Clin Periodontol. 2008 Sep;35(8 Suppl):216-40. doi: 10.1111/j.1600-051X.2008.01272.x.

    PMID: 18724852BACKGROUND
  • Thoma DS, Haas R, Tutak M, Garcia A, Schincaglia GP, Hammerle CH. Randomized controlled multicentre study comparing short dental implants (6 mm) versus longer dental implants (11-15 mm) in combination with sinus floor elevation procedures. Part 1: demographics and patient-reported outcomes at 1 year of loading. J Clin Periodontol. 2015 Jan;42(1):72-80. doi: 10.1111/jcpe.12323. Epub 2014 Dec 26.

    PMID: 25418606BACKGROUND
  • Zhang XM, Shi JY, Gu YX, Qiao SC, Mo JJ, Lai HC. Clinical Investigation and Patient Satisfaction of Short Implants Versus Longer Implants with Osteotome Sinus Floor Elevation in Atrophic Posterior Maxillae: A Pilot Randomized Trial. Clin Implant Dent Relat Res. 2017 Feb;19(1):161-166. doi: 10.1111/cid.12435. Epub 2016 Jul 8.

  • Shi JY, Gu YX, Qiao SC, Zhuang LF, Zhang XM, Lai HC. Clinical evaluation of short 6-mm implants alone, short 8-mm implants combined with osteotome sinus floor elevation and standard 10-mm implants combined with osteotome sinus floor elevation in posterior maxillae: study protocol for a randomized controlled trial. Trials. 2015 Jul 30;16:324. doi: 10.1186/s13063-015-0853-4.

MeSH Terms

Conditions

Jaw, Edentulous, Partially

Condition Hierarchy (Ancestors)

Jaw, EdentulousJaw DiseasesMusculoskeletal DiseasesStomatognathic DiseasesMouth, EdentulousMouth DiseasesTooth Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Doctor, Department of oral and maxillofacial implants

Study Record Dates

First Submitted

January 19, 2015

First Posted

January 29, 2015

Study Start

March 1, 2015

Primary Completion

March 1, 2017

Study Completion

March 1, 2017

Last Updated

May 16, 2019

Record last verified: 2019-05

Locations