NCT02350036

Brief Summary

50 pregnant females were divided in two groups, twenty five as a control group and twenty five as high risk group; they were subjected to uterine artery Doppler, measurement of maternal serum and detection of (MTHFR) gene polymorphisms in first trimester at 11 to 14 weeks of gestation, all pregnancies were followed until 40 weeks for development of pre-eclampsia

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

January 26, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 29, 2015

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

March 21, 2017

Status Verified

March 1, 2017

Enrollment Period

1.9 years

First QC Date

January 26, 2015

Last Update Submit

March 18, 2017

Conditions

Preeclampsia

Keywords

Preeclampsiaplacental protein 13Uterine artery doppler

Outcome Measures

Primary Outcomes (1)

  • development of preeclampsia

    40 weeks pregnancy

Study Arms (2)

preeclmapsia

women developed preeclampsia. ultrasound monitoring and uterine artery Doppler

Other: ultrasound monitoring

control

women with normal blood pressure all through pregnancy. ultrasound monitoring and uterine artery Doppler

Other: ultrasound monitoring

Interventions

ultrasound monitoringOTHER

Uterine artery Doppler assessment

controlpreeclmapsia

Eligibility Criteria

Age20 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

pregnant women at 11 to 14 weeks of gestation

You may qualify if:

  • pregnant women at 11 to 14 weeks of gestation

You may not qualify if:

  • fetal anomalies other medical diseases as diabetes mellitus, renal or liver diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kasr Alainy medical school

Cairo, Cairo Governorate, 12151, Egypt

Location

MeSH Terms

Conditions

Pre-Eclampsia

Condition Hierarchy (Ancestors)

Hypertension, Pregnancy-InducedPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Study Officials

  • Ahmed Maged

    Kasr Alainy medical school

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Target Duration
9 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

January 26, 2015

First Posted

January 29, 2015

Study Start

January 1, 2015

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

March 21, 2017

Record last verified: 2017-03

Locations

EG(1)