Androgens Level in the Third Trimester of Pregnancy in Patients With Preeclampsia

NCT02992145 | Completed DMC

• 1 other identifier: AinShams MH 01
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare between androgens level (serum total and free testosterone) in women with preeclampsia and normal ones in the third trimester of pregnancy (28-40 weeks).

Conditions

Pre-Eclampsia

Outcome Measures

Primary Outcomes (1)

• Total and free testosterone level

  Higher in preeclamptic patients than normal pregnant ladies

  9 months

Study Arms (2)

Case group: This group will include forty (40) preeclampt

Control group: This group will include forty (40) normoten

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Study Site: Ain Shams University Maternity Hospital Study Design: This study is a case control study. Study Population: Patients will be divided into two groups: Case group: This group will include forty (40) preeclamptic patients at the third trimester (28-40 weeks) admitted at Ain Shams University Maternity Hospital. Control group: This group will include forty (40) normotensive pregnant women at term admitted at Ain Shams University Maternity Hospital.

You may qualify if:

• Pregnant women (primigravidas) at third trimester i.e. 28-40 weeks.
• Age between 20 and 35 years old.
• Live fetus.
• Having no history of pregestational hypertension.
• Having no history of diseases associated with hormone disorders (thyroid gland disorders, DM, hyperprolactinemia or polycystic ovary syndrome).
• During their pregnancy they did not receive antihypertensive medications.
• Nonsmoker.

You may not qualify if:

• First and second trimester pregnant women. 2- Women younger than 20 years old and older than 35 years old 3- Intrauterine fetal death. 4- History of pregestational hypertension. 5- History of hormonal disorders (thyroid gland disorders and hyperprolactinemia).
• Smoker. 7- Polycystic ovary syndrome. 8- Signs or symptoms of hyper-androgenism (hirsutism, acne, oily skin, etc.). 9- Diabetes mellitus. 10- Drug use except ordinary supplementation (iron, folic acid).

Sponsors & Collaborators

• Ain Shams Maternity Hospital: lead

Study Sites (1)

Ain Shams Maternity Hospital-Faculty of Medicine- Ain Shams University

Cairo Governorate, Cairo Governorate, 00202, Egypt

Location

Related Publications (1)

• https://www.ncbi.nlm.nih.gov/pubmed/12746983

  RESULT

MeSH Terms

Conditions

Pre-Eclampsia

Condition Hierarchy (Ancestors)

Hypertension, Pregnancy-Induced; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Study Officials

• Noha H Rabei, Professor of Obs&Gyn

  Ain Shams Maternity Hospital

  STUDY CHAIR

• Malames M Faisal, Lecturer of Obs&Gyna

  Ain Shams Maternity Hospital

  STUDY DIRECTOR

• Hoda E Abd elwahab, Fellow of medical tests

  Ain Shams Hospitals

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Obstetrics and gynaecology resident

Study Record Dates

• First Submitted: December 12, 2016
• First Posted: December 14, 2016
• Study Start: March 1, 2016
• Primary Completion: December 1, 2016
• Study Completion: December 1, 2016
• Last Updated: December 16, 2016

Record last verified: 2016-12

Locations

EG (1)