Breast Tumor Oxygenation During Exercise

NCT02340468 | Withdrawn

• 1 other identifier: 20141505
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

In the field of cancer treatment, it is generally accepted that the enhancement of oxygen delivery to tumors can augment the effect of anti-cancer therapies. In the case of chemotherapy, this enhancement might lead to a larger amount of a given dose of treatment reaching the tumor and having an effect.

Conditions

Breast Tumor

Outcome Measures

Primary Outcomes (1)

• Measure breast tumor oxygenation

  up to 12 weeks

Interventions

diffuse optical spectroscopy DEVICE

diffuse optical spectroscopy

Eligibility Criteria

• Age: 21 Years - 70 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Study population will be recruited from an outpatient at UC Irvine Health

You may qualify if:

• Tumor group, female, Greater than 21 years of age but less than 70 years of age, Current diagnosis of breast cancer stage 0 - IV or radiologically suspicious for breast cancer BI-RADS score 4 or 5.
• Control group,Female, Greater than 21 years of age but less than 70 years of age, Not currently diagnosed with breast cancer

You may not qualify if:

• Under 21 years of age, Pregnant or breastfeeding, Contraindications for moderate exercise, history of heart, pulmonary, or musculoskeletal disease; physician instructions to restrict physical activity.

Sponsors & Collaborators

• University of California, Irvine: lead
• Beckman Laser Institute University of California Irvine: collaborator

Study Sites (1)

Beckman Laser Institute Medical Clinic

Irvine, California, 92612, United States

Location

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Bruce Tromberg, PhD

  Beckman Laser Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Bruce Tromberg,Ph.D.,Director, Beckman Laser Institute and Medical Clinic and Professor, Departments of Biomedical Engineering and Surgery

Study Record Dates

• First Submitted: January 13, 2015
• First Posted: January 16, 2015
• Study Start: April 1, 2015
• Primary Completion: January 1, 2018
• Study Completion: January 1, 2018
• Last Updated: November 1, 2022

Record last verified: 2022-10

Locations

US (1)