NCT02327897|Recruiting
NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
Natural History of Asthma With Longitudinal Environmental Sampling
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Natural History of Asthma With Longitudinal Environmental Sampling
Sponsor study identifier
Secondary identifiers
observational
400
1 country
1
Study Start
September 10, 2015
Actual (reported)Primary Completion
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Background: \- Asthma is a serious clinical and public health problem. Researchers want to collect data to better understand how bacteria and other things in the environment can affect people's asthma. Eligibility: \- Nonsmoking adults age 18 - 60 who have moderate to severe asthma. Design:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 30, 2014
Actual (reported)December 31, 2014
Actual (reported)September 10, 2015
Actual (reported)April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
The overall goal is to study the natural history of atopic asthma, focusing on moderate to severe asthma. The primary objective is to collect prospective data and samples for future use to better understand the interaction between environmental ...
Results will be evaluated in the context of the environmental exposures, clinical outcomes (symptoms, exacerbations, and quality of life), and response to therapy.
End of Study
study group
controls
Participants will be recruited from the population at large, including asthmatic participants who visit the CRU for on-going studies. Participants who have successfully completed other CRU studies may be recruited directly for this study. The study will be registered on clinicaltrials.gov. Local public health departments and other clinics may be contacted for help with recruitment of individuals with moderate to severe atopic asthma. In addition, if needed, the study may be advertised in local media outlets.
NIEHS Clinical Research Unit (CRU)
Research Triangle Park, North Carolina, 27709, United States
Stavros Garantziotis, M.D.
National Institute of Environmental Health Sciences (NIEHS)
First Submitted
December 30, 2014
First Posted
December 31, 2014
Study Start
September 10, 2015
Actual (reported)Primary Completion
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
TGF-(Beta) and Susceptibility to RSV
Contact the study team to confirm eligibility.
Study Completion
April 1, 2030
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
October 27, 2026
Record last verified: 2026-02-19
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Source: ClinicalTrials.gov.
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