Evaluation of the Role of Follicular Sensitivity Index in the Prediction of IVF/ICSI Outcome
1 other identifier
observational
10,000
1 country
1
Brief Summary
Records of women who had in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI) in Dar AlTeb sub-fertility center will be reviewed and the follicular sensitivity index (FSI) will be calculated and correlated with pregnancy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2014
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2014
CompletedFirst Submitted
Initial submission to the registry
December 12, 2014
CompletedFirst Posted
Study publicly available on registry
December 17, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2016
CompletedApril 22, 2019
April 1, 2019
1.8 years
December 12, 2014
April 18, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Clinical Pregnancy
FSI values will be classified into 3 groups: High, moderate and low. The proportion of women achieving a clinical pregnancy will be compared among the 3 groups. clinical pregnancy will be defined as the presence of an intrauterine gestational sac 5 weeks after embryo transfer.
5 weeks after embryo transfer
Secondary Outcomes (1)
Number of retrieved oocytes
one hour after ovum pick-up
Study Arms (1)
Subfertility without polycystic ovarian syndrome
The records of all women with infertility who had IVF/ICSI without polycystic ovarian syndrome (PCO) will be reviewed
Interventions
records of women who had ICSI will be reviewed and analysed for determining FSI
Eligibility Criteria
The records of women who had IVF/ICSI without PCO will be reviewed to calculate the FSI.
You may qualify if:
- IVF/ICSI
You may not qualify if:
- Missing data
- Cancelled cycles.
- Polycystic ovarian syndrome.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Dar AlTeb subfertility centre
Cairo, Egypt
Related Publications (3)
Zhang N, Hao CF, Zhuang LL, Liu XY, Gu HF, Liu S, Chen ZJ. Prediction of IVF/ICSI outcome based on the follicular output rate. Reprod Biomed Online. 2013 Aug;27(2):147-53. doi: 10.1016/j.rbmo.2013.04.012. Epub 2013 May 4.
PMID: 23768619BACKGROUNDBroer SL, Mol BW, Hendriks D, Broekmans FJ. The role of antimullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count. Fertil Steril. 2009 Mar;91(3):705-14. doi: 10.1016/j.fertnstert.2007.12.013. Epub 2008 Mar 5.
PMID: 18321493BACKGROUNDMelo MA, Garrido N, Alvarez C, Bellver J, Meseguer M, Pellicer A, Remohi J. Antral follicle count (AFC) can be used in the prediction of ovarian response but cannot predict the oocyte/embryo quality or the in vitro fertilization outcome in an egg donation program. Fertil Steril. 2009 Jan;91(1):148-56. doi: 10.1016/j.fertnstert.2007.11.042. Epub 2008 May 2.
PMID: 18455166BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of Gynecology and Obstetrics
Study Record Dates
First Submitted
December 12, 2014
First Posted
December 17, 2014
Study Start
December 1, 2014
Primary Completion
October 1, 2016
Study Completion
October 1, 2016
Last Updated
April 22, 2019
Record last verified: 2019-04