NCT02317835

Brief Summary

To evaluate a recently developed non-invasive infrared thermal camera called Diabetic Foot Ulcer Prevention System (DFUPS) in a clinical setting by studying healthy volunteers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
105

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Jul 2015

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 10, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 17, 2014

Completed
7 months until next milestone

Study Start

First participant enrolled

July 1, 2015

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
Last Updated

June 9, 2016

Status Verified

June 1, 2016

Enrollment Period

5 months

First QC Date

December 10, 2014

Last Update Submit

June 8, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Detection of hot spots on a foot thermal map image

    9 months

Study Arms (1)

Study in healthy volunteers

OTHER

Skin foot temperature measurement by DFUPS device

Device: DFUPS

Interventions

DFUPSDEVICE

The DFUPS device is a two-camera instrument for capturing images of feet

Study in healthy volunteers

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 18 years or older
  • Has no history of diabetes
  • Has no previous history of foot ulceration
  • Has no previous history of foot surgery
  • Has palpable foot pulses on both feet (palpable posterior tibial artery pulse OR dorsalis pedis artery pulse OR both)
  • Has no history of peripheral neuropathy
  • Has no history of peripheral arterial disease
  • Must be able to provide meaningful written informed consent for the study

You may not qualify if:

  • Has active foot ulceration and infection
  • Has foot deformity which in the opinion of the Investigator, would interfere with interpreting the results of the study
  • Has any uncontrolled illness that, in the opinion of the Investigator, would interfere with interpreting the results of the study
  • Has an implantable electronic device
  • Is aged \<18

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

King's College Hospital

London, SE5 9RS, United Kingdom

Location

The Pennine Acute Hospitals NHS Trust

Manchester, M9 4BE, United Kingdom

Location

The Newcastle upon Tyne Hospitals

Newcastle upon Tyne, NE3 3HD, United Kingdom

Location

Related Publications (1)

  • Petrova NL, Whittam A, MacDonald A, Ainarkar S, Donaldson AN, Bevans J, Allen J, Plassmann P, Kluwe B, Ring F, Rogers L, Simpson R, Machin G, Edmonds ME. Reliability of a novel thermal imaging system for temperature assessment of healthy feet. J Foot Ankle Res. 2018 May 30;11:22. doi: 10.1186/s13047-018-0266-1. eCollection 2018.

MeSH Terms

Conditions

Diabetic Foot

Condition Hierarchy (Ancestors)

Diabetic AngiopathiesVascular DiseasesCardiovascular DiseasesFoot UlcerLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue DiseasesDiabetes ComplicationsDiabetes MellitusEndocrine System DiseasesDiabetic Neuropathies

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NA
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 10, 2014

First Posted

December 17, 2014

Study Start

July 1, 2015

Primary Completion

December 1, 2015

Study Completion

April 1, 2016

Last Updated

June 9, 2016

Record last verified: 2016-06

Locations