The Diagnostic Performance of Tilt Test in Athletes

NCT02316860 | Completed

• 1 other identifier: sportscardiology
• Study Type: interventional
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt. Moreover, the investigators try to apply a novel algorithm for the improvement of diagnostic yield of tilt test in athletes.

Conditions

Syncope

Outcome Measures

Primary Outcomes (1)

• sensitivity and specificity of tilt test in athletes as measured by the occurence of syncope/presyncope during tilt test

  sensitivity = number of subjects with syncope/presyncope during tilt test/ number of subjects with a history of reflex syncope, specificity = number of subjects without syncope/presyncope during tilt test/ number of subjects without history of reflex syncope

  30 min

Secondary Outcomes (3)

• Parameters of haemodynamics during tilt test

  30 min

• Parameters of heart rate variability during tilt test

  30 min

• Parameters of baroreflex sensitivity during tilt test

  30 min

Study Arms (2)

History of reflex syncope

OTHER

Passive tilt test in athletes with a history of reflex syncope

Other: Passive tilt test

No history of reflex syncope

OTHER

Passive tilt test in athletes without history of reflex syncope

Other: Passive tilt test

Interventions

Passive tilt test OTHER

Passive tilt test (without pharmacological provocation). After a horizontal supine rest period of 5 min, the tilt table was inclined at 60° head-up position for 30 min. A positive response was defined according to the European Society of Cardiology guidelines for the diagnosis and management of syncope

History of reflex syncope; No history of reflex syncope

Eligibility Criteria

• Age: 14 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• years old,
• more than 5 years of exercise training experience and competition at a regional level at different sports

You may not qualify if:

• smoking,
• recent alcohol consumption,
• presence of any chronic disease and use of drugs

Sponsors & Collaborators

• Aristotle University Of Thessaloniki: lead

Study Sites (1)

Laboratory of Sports Medicine, Sports Medicine Division, Aristotle University of Thessaloniki, Thessaloniki, Greece

Thessaloniki, 54622, Greece

Location

MeSH Terms

Conditions

Syncope

Condition Hierarchy (Ancestors)

Unconsciousness; Consciousness Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Evangelia Kouidi, Professor

  Laboratory of Sports Medicine, Sports Medicine Division, Aristotle University of Thessaloniki, Thessaloniki, Greece

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Sports Medicine-Cardiologist

Study Record Dates

• First Submitted: December 6, 2014
• First Posted: December 15, 2014
• Study Start: October 1, 2014
• Primary Completion: December 1, 2014
• Study Completion: December 1, 2014
• Last Updated: October 26, 2017

Record last verified: 2017-10

Locations

GR (1)