NCT02307292

Brief Summary

This is a prospective, non-randomized post market surveillance registry designed to document the clinical Performance in Routine clinical practice of the POLARIS Peripheral Vascular Self Expanding Stent System

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2014

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 18, 2014

Completed
13 days until next milestone

Study Start

First participant enrolled

December 1, 2014

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 4, 2014

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2017

Completed
Last Updated

January 12, 2015

Status Verified

January 1, 2015

Enrollment Period

2.3 years

First QC Date

November 18, 2014

Last Update Submit

January 9, 2015

Conditions

Keywords

Superficial femoral arterySelf Expanding Stent System

Outcome Measures

Primary Outcomes (1)

  • Freedom from target lesion revascularization

    Clinically driven

    at 12 months

Secondary Outcomes (5)

  • Binary restenosis/ reocclusion

    at 12 months

  • Target limb amputation at the index leg (major and minor separately)

    at 12 months

  • All-cause death

    at 12 months

  • Change in resting ankle brachial index (ABI)

    From baseline to 12 and 24 months

  • Change in Rutherford Classification

    From baseline to 12 and 24 months

Interventions

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with single significant (\>50%) superficial femoral artery disease

You may qualify if:

  • Age \>18 years
  • Single target de novo superficial femoral artery lesion (angiographic evidence of \>50% Stenosis or occlusion) by visual estimate
  • Rutherford category II-IV
  • At least one patent outflow artery to the ankle.
  • Patient signed the informed consent

You may not qualify if:

  • Patient with acute or subacute Thrombus
  • Patients with hyperkoagulopathy
  • Patients with Stenosis or occlusion where lesion crossing with guide wire is not possible
  • Pregnancy or positive pregnancy test
  • Previous enrolment in this Trial or other industrial Trials
  • Patient´s inability to fully cooperate with the registry protocol Patient with cancer Treatment (life expectancy less than 2 years) Patients with renal failure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HGZ Bad Bevensen, Department of Angiology

Bad Bevensen, 29549, Germany

RECRUITING

Related Publications (1)

  • Thieme M, Arjumand J, Spanagel M, Tepe G, Blessing E, Kroeg B, Reichert V, Betge S, Wickenhofer R, Tessarek J, Ingwersen M, Krankenberg H. Stents With Torsional Strength for Superficial Femoral Artery Disease: The Prospective Q3-Registry. J Endovasc Ther. 2022 Dec;29(6):904-912. doi: 10.1177/15266028211067726. Epub 2022 Jan 7.

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular Diseases

Study Officials

  • Hans Krankenberg, MD,PhD

    Cardiovascular Center Bad Bevensen, Department of Angiology

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sigrid Krimmer-Quendler, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
24 Months
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD PhD

Study Record Dates

First Submitted

November 18, 2014

First Posted

December 4, 2014

Study Start

December 1, 2014

Primary Completion

April 1, 2017

Study Completion

April 1, 2017

Last Updated

January 12, 2015

Record last verified: 2015-01

Locations