NCT02717104

Brief Summary

The purpose of the registry is to assess the clinical use and safety of the LUTONIX Drug Coated Balloon Catheter in a heterogeneous patient population in real world clinical practice.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
249

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2015

Longer than P75 for all trials

Geographic Reach
1 country

16 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 20, 2015

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

March 16, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 23, 2016

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2018

Completed
2.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

July 17, 2020

Status Verified

July 1, 2020

Enrollment Period

2.5 years

First QC Date

March 16, 2016

Last Update Submit

July 16, 2020

Conditions

Keywords

femoropopliteal

Outcome Measures

Primary Outcomes (4)

  • Freedom from Target Lesion Revascularization

    12 months

  • Freedom from Target Vessel and Target Lesion Revascularization

    30 days

  • Freedom from Major Amputation and Major Reintervention of index limb

    30 days

  • Freedom from device- and procedure-related death

    30 days

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

General patient pool of participating hospitals or clinics

You may qualify if:

  • ≥19 years of age
  • Rutherford Clinical Category ≥4
  • Patient or Legally Authorized Representative is willing to provide informed consent and comply with the required follow-up
  • Stenotic or obstructive vascular lesions in femoropopliteal artery(s)
  • Lesion(s) can be treated with available LUTONIX Drug Coated Balloon Catheter device size matrix per current IFU
  • At least one patent native outflow artery to the ankle free from significant lesion (≥50% stenosis) as confirmed by angiography (treatment of outflow disease is NOT permitted; treatment of in-flow disease is permitted prior to treatment with the LUTONIX Drug Coated PTA Dilatation Catheter)

You may not qualify if:

  • Patient is currently participating in an active phase of another investigational drug or device study
  • Inability to take recommended medications as stated in the IFU or non-controllable allergy to contrast
  • Known inadequate distal outflow or planned future (within 30 days) treatment of vascular disease distal to the target lesion

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (16)

Hallym University Sacred Heart Hospital

Anyang-si, Gyeonggi-do, 431-796, South Korea

Location

Soonchunjyang University Hospital

Bucheon-si, Gyeonggi-do, South Korea

Location

Myongji Hospital

Goyang-si, Gyeonggi-do, 412-270, South Korea

Location

Kangbuk Samsung Hospital

Seoul, Jongno-gu, South Korea

Location

Busan Veterans Hospital

Busan, South Korea

Location

Inje University Busan Park Hospital

Busan, South Korea

Location

Keimyung University Dongsan Medical Center

Daegu, 700-712, South Korea

Location

YeungNam University Medical Center

Daegu, 705-703, South Korea

Location

Chungnam National University Hospital

Daejeon, 301-721, South Korea

Location

Chonnam National University Hospital

Gwangju, 501-757, South Korea

Location

Inha University Hospital

Incheon, 400-711, South Korea

Location

Seoul National University Hospital

Seoul, 110-799, South Korea

Location

Seoul St. Mary's Hospital

Seoul, 137-040, South Korea

Location

Asan Medical Center

Seoul, 138-736, South Korea

Location

Konkuk University Hospital

Seoul, 143-729, South Korea

Location

Ajou University Hospital

Suwon, 443-380, South Korea

Location

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular Diseases

Study Officials

  • Jae Kyu Kim, MD

    Chonnam National University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
24 Months
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 16, 2016

First Posted

March 23, 2016

Study Start

August 20, 2015

Primary Completion

March 1, 2018

Study Completion

June 1, 2020

Last Updated

July 17, 2020

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations