Different Endurance Training Protocols in Cardiac Patients
Effects of Different Endurance Training Protocols on Physical Performance in Cardiac Patients
1 other identifier
interventional
52
1 country
1
Brief Summary
It is the aim of our study to compare the effects of 6 and/or 2 years of either HIT (carried out at correctly assessed 85-95% of maximal heart rate), pyramid, or continuous endurance training, on changes of physical exercise capacity in cardiac patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable coronary-artery-disease
Started Jan 2014
Longer than P75 for not_applicable coronary-artery-disease
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
November 25, 2014
CompletedFirst Posted
Study publicly available on registry
November 27, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2020
CompletedJanuary 29, 2021
January 1, 2021
4.9 years
November 25, 2014
January 28, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Physical work capacity (PWC)
PWC will be measured by graded exercise testing on cycle ergometer.
6 weeks or 36 weeks
Secondary Outcomes (7)
Heart rate
6 weeks or 36 weeks
Blood pressure
6 weeks or 36 weeks
Lactate Thresholds
6 weeks or 36 weeks
Metabolical and cellular blood parameter
6 weeks or 36 weeks
BMI
6 weeks or 36 weeks
- +2 more secondary outcomes
Study Arms (3)
Continuous Endurance training
ACTIVE COMPARATOREndurance training with constant work load 31min at 65-75% maximal heart rate (HRmax)
Pyramid Training
EXPERIMENTALOne pyramid consists of 8 one-minute blocks. Those are grouped starting with one block of 70-75% HRmax, followed by one block at 75-80% HRmax and another one at 80-85% HRmax. The top of the pyramid are 2 blocks of 85-90% HRmax. Intensity is lowered afterwards with one block of 80-85% HRmax, followed by one block at 75-80% HRmax and last one at 70-75% HRmax. Two more pyramids follow, each divided by 2min of active recovery at 65-70% HRmax, making it a total of 28min.
High-intensity intervall training
EXPERIMENTALHIT: 4x4 min intervals at85-95% HRmax divided by 3x3min of active recovery at 60-70% HRmax, making it a total of 25min.
Interventions
Endurance training with constant work load 31min at 65-75% Hrmax
One pyramid consists of 8 one-minute blocks. Those are grouped starting with one block of 70-75% HRmax, followed by one block at 75-80% HRmax and another one at 80-85% HRmax. The top of the pyramid are 2 blocks of 85-90% HRmax. Intensity is lowered afterwards with one block of 80-85% HRmax, followed by one block at 75-80% HRmax and last one at 70-75% HRmax. Two more pyramids follow, each divided by 2min of active recovery at 65-70% HRmax, making it a total of 28min.
HIT: 4x4 min intervals at85-95% HRmax divided by 3x3min of active recovery at 60-70% HRmax, making it a total of 25min.
Eligibility Criteria
You may qualify if:
- acute coronary syndrome (STEMI - NONSTEMI)
- aortocoronary bypass surgery
- percutaneous coronary intervention (PCI)
- state after stable coronary heart disease
- state after heart surgeries
- state after myo-, endo-, or pericarditis
- state after heart- or lung-transplantation
- state after heart failure
- state after pulmonary hypertension
- state after peripheral venous disease
- state after electrophysiological surgery
- state after implantation of an implantable cardioverter or difibrillator
- Patients at high risk
- Patients with cardiac dysrhythmias or sudden death
You may not qualify if:
- unstable angina pectoris
- Heart failure (NYHA IV)
- acute myo-, endo-, or pericarditis or other infections
- pulmonary-arterial embolism or phlebothrombosis within 6 months
- hemodynamic instable dysrhythmias
- hypertrophic cardiomyopathy
- medical conditions which prevent patients from complying with the exercise program
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University
Salzburg, 5020, Austria
Related Publications (1)
Mayr B, Muller EE, Schafer C, Droese S, Schonfelder M, Niebauer J. Exercise-induced changes in miRNA expression in coronary artery disease. Clin Chem Lab Med. 2021 May 12;59(10):1719-1727. doi: 10.1515/cclm-2021-0164. Print 2021 Sep 27.
PMID: 33977686DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Prof. Josef Niebauer, M.D, PhD,MBA
Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Head of institute
Study Record Dates
First Submitted
November 25, 2014
First Posted
November 27, 2014
Study Start
January 1, 2014
Primary Completion
December 1, 2018
Study Completion
December 1, 2020
Last Updated
January 29, 2021
Record last verified: 2021-01