Cognitive Behavior Therapy for Atopic Dermatitis

NCT02302625 | Completed

• 1 other identifier: CBT atopic
• Study Type: interventional
• Target: 9
• Locations: 1 country
• Sites: 1

Brief Summary

Atopic dermatitis is an inflammatory skin disease characterized by itching, dry skin and recurrent inflammatory eczema. It is one of the most common skin diseases and is associated with reduced quality of life, functional impairment and sleep difficulties. The present study aims to investigate a new exposure-based cognitive behavioral psychological treatment for the disorder. The trial is a small scale open trial (n=25) with assessments at baseline, post-treatment and 6-month follow-up. The primary outcome is the SCORAD.

Conditions

Atopic Dermatitis

Keywords

Cognitive behavior therapy

Outcome Measures

Primary Outcomes (1)

• Severity Scoring of Atopic Dermatitis index (SCORAD)

  Change from baseline to 10 weeks follow-up and 6-month follow-up

Secondary Outcomes (6)

• Beck Anxiety Inventory

  Change from baseline to 10 weeks follow-up and 6-month follow-up

• Montgomery-Åsberg Depression Rating Scale-Self-rated

  Change from baseline to 10 weeks follow-up and 6-month follow-up

• Quality of Life Inventory

  Change from baseline to 10 weeks follow-up and 6-month follow-up

• Alcohol Disorders Identification Test

  Baseline only

• SRH-5

  Change from baseline to 10 weeks follow-up and 6-month follow-up

Study Arms (1)

Cognitive behavior therapy

EXPERIMENTAL

Cognitive behavior therapy based on exposure and response prevention. The treatment also incorporates mindfulness training as a means to increasing tolerance for aversive thoughts and emotions associated with AD. The treatment is delivered by a licensed psychologist and comprises 10 individual weekly sessions.

Behavioral: Cognitive behavior therapy

Interventions

Cognitive behavior therapy BEHAVIORAL

Cognitive behavior therapy based on exposure and response prevention. The treatment also incorporates mindfulness training as a means to increasing tolerance for aversive thoughts and emotions associated with AD. The treatment is delivered by a licensed psychologist and comprises 10 individual weekly sessions.

Cognitive behavior therapy

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of AD with at least moderate severity
• AD for at least 6 months
• Age 18-65
• Ability to read and write in Swedish

You may not qualify if:

• Serious psychiatric illness
• Concurrent light treatment or peroral treatment for AD
• Pregnancy
• Other concurrent or recently finished psychological treatment for AD

Sponsors & Collaborators

• Karolinska Institutet: lead

Study Sites (1)

Karolinska Institutet and Gustavsberg primary care center

Stockholm, Stockholm County, 13440, Sweden

Location

MeSH Terms

Conditions

Dermatitis, Atopic

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Skin Diseases, Genetic; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Dermatitis; Skin Diseases; Skin and Connective Tissue Diseases; Skin Diseases, Eczematous; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Erik Hedman

  Karolinska Institutet

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Phd, psychologist

Study Record Dates

• First Submitted: November 19, 2014
• First Posted: November 27, 2014
• Study Start: November 1, 2014
• Primary Completion: February 1, 2016
• Study Completion: February 1, 2016
• Last Updated: March 3, 2016

Record last verified: 2016-03

Locations

SE (1)