NCT02298972

Brief Summary

This study evaluates the value of a nursing symptom support en selfmanagement intervention for adult patients with cancer treated with chemotherapy. Using a prospective sequential design with a comparison group who receives standard care and a (later) intervention group who gets the nursing intervention, we will evaluate the effect of this nursing intervention on overall symptom distress (primary outcome) and other measures of symptom burden, self-efficacy, outcome expectations and self-care. By conducting sem-structured interviews with some participants of the intervention group, we will study the patient experience of the intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
143

participants targeted

Target at P50-P75 for not_applicable cancer

Timeline
Completed

Started Oct 2014

Shorter than P25 for not_applicable cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 17, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 24, 2014

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

October 26, 2016

Status Verified

October 1, 2016

Enrollment Period

9 months

First QC Date

November 17, 2014

Last Update Submit

October 24, 2016

Conditions

Outcome Measures

Primary Outcomes (2)

  • Overall symptom distress

    Summed symptom distress as self-reported on the Symptom Burden Questionnaire

    Longitudinal, during first 3 months after start of treatment

  • Overall symptom severity

    Summed symptom severity as self-reported on the Symptom Burden Questionnaire

    Longitudinal, during first 3 months after start of treatment

Secondary Outcomes (3)

  • Total self-efficacy score

    Day 43 of treatment (+/- 1 week)

  • Total outcome expectations score

    Day 43 of treatment (+/- 1 week)

  • Total self-care score

    Day 85 of treatment (+/- 1 week)

Study Arms (2)

Comparison group

NO INTERVENTION

The comparison group will receive standard care.

Intervention group

ACTIVE COMPARATOR

After completion of the comparison group, new patients starting chemotherapy treatment will be offered this study. Study participants will receive the nurse support and selfmanagement intervention.

Behavioral: Nurse support and selfmanagement intervention

Interventions

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients starting first line treatment with (intravenous) chemotherapy
  • Ambulatory patients or patients who receive their treatment during short hospital stays
  • Regardless of type of cancer, treatment or treatment intention (curative or palliative)
  • Who understand sufficiently Dutch to fill out questionnaires
  • Who sign informed consent for their participation in the study

You may not qualify if:

  • Oral anticancer treatment
  • Concomitant chemoradiotherapy
  • Breast cancer patients who receive nurse counseling throughout their therapy
  • Experimental therapy in the context of a clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UZ Leuven

Leuven, Belgium

Location

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Nurse Specialist oncology

Study Record Dates

First Submitted

November 17, 2014

First Posted

November 24, 2014

Study Start

October 1, 2014

Primary Completion

July 1, 2015

Study Completion

September 1, 2015

Last Updated

October 26, 2016

Record last verified: 2016-10

Locations