NCT02297841

Brief Summary

Determine the ability of the study material (personal lubricant) to cause sensitization by repeated topical application to the skin of humans under controlled patch test conditions.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
209

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2014

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2014

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

November 17, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 21, 2014

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

October 5, 2016

Completed
Last Updated

October 5, 2016

Status Verified

September 1, 2016

Enrollment Period

1 month

First QC Date

November 17, 2014

Results QC Date

July 19, 2016

Last Update Submit

September 14, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Adverse Events as a Measure of Safety and Tolerability

    24, 48, and 72 hours after patch application

Study Arms (1)

Human Repeat Insult Patch Test

EXPERIMENTAL

Approximately 0.2ml of each intervention (Experimental: Novel lubricant Miami Fragrance, Experimental: Novel lubricant Miami no Fragrance, KY Liquid lubricant, Astroglide Gel lubricant) was applied to an occlusive patch and applied to participant's back.

Device: Experimental: Novel lubricant Miami FragranceDevice: Experimental: Novel lubricant Miami no FragranceDevice: KY Liquid lubricantDevice: Astroglide Gel lubricant

Interventions

Human Repeat Insult Patch Test
Human Repeat Insult Patch Test
Human Repeat Insult Patch Test
Human Repeat Insult Patch Test

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • In general good health
  • Free of any systemic or dermatologic disorder which, in the opinion of the investigative personnel, will interfere with the study results or increase the risk of adverse events
  • Are of any skin type or race, providing the skin pigmentation will allow discernment of erythema
  • Complete a medical screening procedure
  • Read, understand, and sign an informed consent agreement

You may not qualify if:

  • Have any visible skin disease at the study site which, in the opinion of the investigative personnel, will interfere with the evaluation
  • Are receiving systemic or topical drugs or medication which, in the opinion of the investigative personnel, will interfere with the study results
  • Have psoriasis and/or active atopic dermatitis/eczema.
  • Are females who are pregnant, planning on getting pregnant during the study, or breast-feeding
  • Have a known sensitivity for cosmetics, skin care products, topical drugs, or any other type of the products, as related to the material being evaluated

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

ErythemaEdema

Condition Hierarchy (Ancestors)

Skin DiseasesSkin and Connective Tissue DiseasesSkin ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Annahita Ghassemi
Organization
Church & Dwight Co., Inc.

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 17, 2014

First Posted

November 21, 2014

Study Start

November 1, 2014

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

October 5, 2016

Results First Posted

October 5, 2016

Record last verified: 2016-09