NCT02293512

Brief Summary

Tinnitus (i.e., ringing in the ears) is currently the most prevalent disability among Veterans. A range of clinical interventions has been created to systematically address the range of issues caused by tinnitus. While numerous interventions purport to promote coping strategies for tinnitus-related problems, few studies directly target and measure coping outcomes. The present pilot study proposes a comparison of coping outcomes after 3 psycho-educational groups: a cognitive-behavioral therapy (CBT) intervention, a Coping Effectiveness Training (CET) intervention, or an Acceptance and Commitment Therapy intervention among Veterans with tinnitus. These groups will be compared to a usual care group among Veterans and civilians with tinnitus. The proposed study will be the first application of CET to tinnitus. The primary goals of this study are to develop a CET protocol for tinnitus and to evaluate the effectiveness of CBT, CET, and ACT interventions to a usual care group. The long-term goal of this study is to improve the quality of life among individuals with tinnitus.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 5, 2014

Completed
13 days until next milestone

First Posted

Study publicly available on registry

November 18, 2014

Completed
10 months until next milestone

Study Start

First participant enrolled

September 1, 2015

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2016

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2016

Completed
1.9 years until next milestone

Results Posted

Study results publicly available

November 5, 2018

Completed
Last Updated

December 24, 2018

Status Verified

December 1, 2018

Enrollment Period

1 year

First QC Date

November 5, 2014

Results QC Date

August 23, 2017

Last Update Submit

December 3, 2018

Conditions

Keywords

TinnitusCopingPsychoeducational intervention

Outcome Measures

Primary Outcomes (1)

  • Coping

    The Brief COPE scale (Carver, 1997) is a widely-used 28-item short form of the COPE Inventory (Carver, Scheier et al., 1989). This instrument measures 14 coping subscales. Each item is scored using a 1-4 frequency scale (i.e., 1= "I haven't been doing this it at all" to 4= "I've been doing this a lot"), where higher scores reflect greater use of the coping strategy. A three-factor structure was used as follows: (a) Engagement coping (EC), including active coping, positive reframing, planning, accepting, and use of humor (items n = 12; score range 12-48); (b) disengagement coping (DC), including self-distancing, denial, behavioral disengagement, and self-blame (items n = 6; score range 6-24); and (c) social support coping (SS), including instrumenal support, emotional support, venting, and religion (items n = 8; score range 8-32).

    Baseline

Study Arms (4)

Coping Effectiveness Training

EXPERIMENTAL

Coping Effectiveness Training (CET) is provided in a 3-session intervention to facilitate coping strategies among individuals with tinnitus. The CET psychoeducational intervention teaches coping skills to increase understanding of stress and coping with tinnitus, and to help individuals better know how to match appropriate coping strategies, based on whether the stressful situation is changeable or not.

Behavioral: Coping Effectiveness Training

Cognitive-behavioral therapy

ACTIVE COMPARATOR

Cognitive-behavioral therapy (CBT) is provided in a 3-session psychoeducational intervention to reduce negative affectivity triggered by tinnitus. CBT treatments for tinnitus target the reduction of psychopathology by altering cognitive distortions, automatic thoughts, and core beliefs, as well as behavioral techniques to reduce physiological arousal.

Behavioral: Cognitive-behavioral therapy

Acceptance and Commitment Therapy

ACTIVE COMPARATOR

Acceptance and Commitment Therapy (ACT) is provided in a 3-session psychoeducational intervention to decrease resistance to tinnitus and increase committed action based on values, despite having tinnitus.

Behavioral: Acceptance and Commitment Therapy

Wait-list control group

NO INTERVENTION

Wait-list control group involves no intervention. This is a 'usual care' group.

Interventions

A CET psychoeducational intervention is provided to increase understanding of stress and coping with tinnitus, and to better learn how to match appropriate coping strategies, based on whether the stressful situation is changeable or not.

Also known as: CET
Coping Effectiveness Training

CBT treatments for tinnitus target the reduction of psychopathology by altering cognitive distortions, automatic thoughts, and core beliefs, as well as behavioral techniques to reduce physiological arousal.

Also known as: CBT
Cognitive-behavioral therapy

An ACT psycho-educational intervention to reduce distress and resistance about having tinnitus and to increase committed actions based on one's values.

Also known as: ACT
Acceptance and Commitment Therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Development Phase (Phase 1)-focus groups:
  • \) Veterans;
  • \) have chronic tinnitus that is sufficiently bothersome to warrant intervention-see below for explanation;
  • \) able to communicate in English;
  • \) willing and able to give written informed consent;
  • \) use hearing aids if needed; and
  • \) have participated in the PTM program at the VA Portland Healthcare System.
  • Testing Phase (Phase 2)-interventions:
  • \) Veterans and civilians;
  • \) have a score of at least 25 on the Tinnitus Functional Index (\[TFI\]; Meikle, J.A. Henry, et al., 2012);
  • \) have two errors or less on a six-item cognitive screening instrument (Callahan, Unverzagt, Hui, Perkins, \& Hendrie, 2002);
  • \) able to communicate in English;
  • \) willing and able to give written informed consent; and
  • \) use hearing aids if needed.

You may not qualify if:

  • Development Phase (Phase 1)-focus groups:
  • nor have any other factor that would preclude full participation in the study.
  • Testing Phase (Phase 2)-interventions:
  • having participated in the PTM program or Phase 1 of this study,
  • or having any other factor that would preclude full participation in the study. Recruitment for Phase 2 will begin in year 1 once the CET protocol is finalized.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Portland Health Care System, Portland, OR

Portland, Oregon, 97239, United States

Location

Related Links

MeSH Terms

Conditions

Tinnitus

Interventions

Cognitive Behavioral TherapyAcceptance and Commitment Therapy

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Limitations and Caveats

One limitation was that only self-report instruments were used, and therefore, social desirability may have influenced the results. Further, while this study involved repeated measures, the sample was small and thus the results should be replicated.

Results Point of Contact

Title
Erin Martz, PhD
Organization
VA Portland Healthcare System

Study Officials

  • Erin C Martz, PhD

    VA Portland Health Care System, Portland, OR

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 5, 2014

First Posted

November 18, 2014

Study Start

September 1, 2015

Primary Completion

August 31, 2016

Study Completion

November 30, 2016

Last Updated

December 24, 2018

Results First Posted

November 5, 2018

Record last verified: 2018-12

Data Sharing

IPD Sharing
Will not share

Locations