NCT02291120

Brief Summary

The objective of the study is to evaluate and compare, clinically and radiographically,the effects of MEDCEM PC and MTA when used as pulp dressings following pulpotomy in human primary molars.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Mar 2014

Typical duration for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2014

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 27, 2014

Completed
5 months until next milestone

First Posted

Study publicly available on registry

November 14, 2014

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

November 14, 2014

Status Verified

November 1, 2014

Enrollment Period

1.6 years

First QC Date

June 27, 2014

Last Update Submit

November 11, 2014

Conditions

Outcome Measures

Primary Outcomes (2)

  • Clinical success

    No pain, no swelling, no fistula or sinus tract, no pathologic mobility

    24 months

  • Radiographic success

    No internal root resorption progressing into the bone, no external root resorption, no furcation and/or periapical bone destruction

    24 months

Study Arms (2)

MTA

ACTIVE COMPARATOR

ProRoot® MTA is a root canal repair material that is a unique improvement over other materials used for root canal repair. Made up of fine hydrophilic particles that set in the presence of water, ProRoot® MTA seals off all pathways between the root canal system and surrounding tissues, significantly reducing bacterial migration. Its excellent compatibility with the dentinal wall allows for a predictable clinical healing response.

Procedure: Pulpotomy

MedCem Portland Cement (PC)

EXPERIMENTAL

MedCem PC is an excellent capping material for cariology on permanent teeth (direct and indirect capping) and in milk tooth endodontics (milk tooth amputation). Is characterized by excellent colour stability and neutrality and does not contain any additional ingredients

Procedure: Pulpotomy

Interventions

PulpotomyPROCEDURE
MTAMedCem Portland Cement (PC)

Eligibility Criteria

Age3 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • healthy children
  • molars showing: symptomless exposure of vital pulp by caries no clinical or radiographic evidence of pulp degeneration (excessive bleeding from the root canal, internal root resorption, inter-radicular and/or furcal bone destruction) the possibility of proper restoration of the teeth no physiological resorption of more than one-third of the root

You may not qualify if:

  • presence of systemic pathology
  • history of allergic reaction to latex, local anaesthetics or to the constituents of the test pulp dressing agents

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universitat Internacional de Catalunya

Sant Cugat del Vallès, Barcelona, 08195, Spain

RECRUITING

MeSH Terms

Interventions

Pulpotomy

Intervention Hierarchy (Ancestors)

EndodonticsDentistry

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master's Program Director in Pediatric Dentistry

Study Record Dates

First Submitted

June 27, 2014

First Posted

November 14, 2014

Study Start

March 1, 2014

Primary Completion

October 1, 2015

Study Completion

December 1, 2016

Last Updated

November 14, 2014

Record last verified: 2014-11

Locations