NCT02286271

Brief Summary

Official statistics report around 1000 deaths due to epilepsy in the UK each year (Hanna et al 2002). Most of these deaths are un-witnessed and in many cases are believed to have been avoidable with timely assistance (Langan et al 2000). A major problem is detecting nocturnal seizures to allow body re-positioning, to maintain an open airway and to administer rescue medication. There are several seizure alarms commercially available but are often unreliable with many false alarms. The aim of this study is to investigate a novel seizure detection system with a unique algorithm.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
117

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2015

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 4, 2014

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 7, 2014

Completed
2 months until next milestone

Study Start

First participant enrolled

January 20, 2015

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2016

Completed
Last Updated

May 8, 2017

Status Verified

August 1, 2016

Enrollment Period

1.9 years

First QC Date

November 4, 2014

Last Update Submit

May 5, 2017

Conditions

Keywords

Seizure detection

Outcome Measures

Primary Outcomes (1)

  • Reliable detection of epileptic seizures (Trigger level to be determined for total seizures)

    Trigger level to be determined for total seizures

    14 months

Secondary Outcomes (1)

  • Reliable detection of epileptic seizures (Trigger level to be determined for different types of seizures.)

    14 months

Eligibility Criteria

Age3 Months+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who are being admitted for electroencephalographic videotelemetry as part of their clinical management of their epilepsy will be invited to participate in the study.

You may qualify if:

  • Frequent epileptic seizures 3 months and older Informed consent for participation

You may not qualify if:

  • Infrequent seizures Attacks are of a non-epileptic nature Younger than 3 months Has an implantable device No informed consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Western General Hospital

Edinburgh, EH4 2XU, United Kingdom

Location

Royal Hospital for Sick Children

Edinburgh, EH9 1LF, United Kingdom

Location

Related Publications (2)

  • Hanna H.J, Black M, Sander J.W.S, Smithson W.H, Appleton R, Brown S, Fish D.R. The National Sentinel Clinical Audit of Epilepsy-Related Death- Death in the Shadows. The Stationery Office. The National Sentinel of Epilepsy-Related Deaths Report 2002 ISBN 0-117-02868-1

    BACKGROUND
  • Langan Y, Nashef L, Sander JW. Sudden unexpected death in epilepsy: a series of witnessed deaths. J Neurol Neurosurg Psychiatry. 2000 Feb;68(2):211-3. doi: 10.1136/jnnp.68.2.211.

    PMID: 10644790BACKGROUND

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Peter AG Sandercock, BA,BM, BCh

    University of Edinburgh

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 4, 2014

First Posted

November 7, 2014

Study Start

January 20, 2015

Primary Completion

December 31, 2016

Study Completion

December 31, 2016

Last Updated

May 8, 2017

Record last verified: 2016-08

Locations