NCT02279030

Brief Summary

The purpose of this study is to assess if Single Photon Emission Computed Tomography (SPECT) demonstrating cardiac innervation can be integrated into current electrophysiology voltage mapping system and provide improved guidance for ablation of PVCs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jun 2015

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 20, 2014

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 30, 2014

Completed
7 months until next milestone

Study Start

First participant enrolled

June 1, 2015

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

February 8, 2022

Status Verified

January 1, 2022

Enrollment Period

4.6 years

First QC Date

October 20, 2014

Last Update Submit

January 25, 2022

Conditions

Premature Ventricular Contractions

Keywords

ablation

Outcome Measures

Primary Outcomes (3)

  • Utilization of MIBG imaging for PVC ablations

    To determine if MIBG imaging provides decreased PVC ablation time

    2 years

  • Decrease PVC occurrence

    Does MIBG imaging allow for treatment that provides improved outcomes in decreasing PVCs

    2 years

  • Increase in Motility

    Do MIBG follow-ups demonstrate an improvement in cardiac motility

    2 years

Interventions

MIBG nuclear scanOTHER

To have scan to help define pathways for PVC ablations.

Also known as: PVC ablations

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients requiring PVC ablation

You may qualify if:

  • Scheduled for PVC ablation

You may not qualify if:

  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Maryland Medical Center

Baltimore, Maryland, 21201, United States

Location

MeSH Terms

Conditions

Ventricular Premature Complexes

Condition Hierarchy (Ancestors)

Cardiac Complexes, PrematureArrhythmias, CardiacHeart DiseasesCardiovascular DiseasesCardiac Conduction System DiseasePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
CARDIAC ELECTROPHYSIOLOGY PHYSICIAN

Study Record Dates

First Submitted

October 20, 2014

First Posted

October 30, 2014

Study Start

June 1, 2015

Primary Completion

December 31, 2019

Study Completion

December 31, 2019

Last Updated

February 8, 2022

Record last verified: 2022-01

Locations

US(1)