NCT02277821

Brief Summary

The action of one Stendo pulsating suit session will be evaluated on 24 patients referred to the hypertension consultations for essential hypertension treated but not stabilized. The effect of one Stendo pulsating suit session system will be mainly assessed on the peripheral cutaneous microcirculation and on the central arterial pressure.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

October 8, 2014

Completed
21 days until next milestone

First Posted

Study publicly available on registry

October 29, 2014

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2015

Completed
Last Updated

May 22, 2015

Status Verified

October 1, 2014

Enrollment Period

9 months

First QC Date

October 8, 2014

Last Update Submit

May 21, 2015

Conditions

Keywords

Essential HypertensionCentral Blood PressureMicrocirculationEndothelium Stimulation

Outcome Measures

Primary Outcomes (1)

  • Peripheral microcirculation measured using Laser Doppler flowmetry

    Change in % of the peripheral cutaneous microcirculation using laser Doppler flowmetry after one Stendo pulsating suit session

    35 minutes after the end of the Stendo session at D1 + 7 jours +/- 3

Secondary Outcomes (2)

  • Humeral arterial pressure

    20 minutes after the end of Stendo session at D1 + 7 jours +/- 3

  • Central blood pressure

    Just after the end of the Stendo session.at D1 + 7 jours +/- 3

Study Arms (1)

Stendo pulsating suit System

EXPERIMENTAL

One 20 minutes Stendo pulsating suit session will be applied to the patient.

Device: Stendo pulsating suit System

Interventions

The Stendo system, a multilayer pulsatile inflatable suit is applied to the lower limbs and the abdomen. This device induces a sequential compartmentalized compression synchronized with each diastolic phase of the cardiac cycle, each phase evolving centripetally (lower limbs to abdomen).

Stendo pulsating suit System

Eligibility Criteria

Age40 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient referred to the Hypertension Hospital Consultation for essential hypertension treated but not stabilized
  • Patient with essential hypertension defined by a brachial arterial pressure of 140 ≤ Systolic Arterial Pressure \< 180 mm Hg and/or 90 ≤ Diastolic Arterial - Pressure \< 110 mm Hg
  • Patients aged more than 40 and less than 70

You may not qualify if:

  • Patient with secondary hypertension
  • Patient with diabetes
  • Patient with complete arrhythmia with atrial fibrillation
  • Patient with an advanced obstructive arterial disease
  • Patient with a recent and progressive deep venous thrombosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hôpital Lariboisière - Service de Physiologie Clinique - Explorations Fonctionnelles

Paris, 75010, France

RECRUITING

MeSH Terms

Conditions

Essential Hypertension

Condition Hierarchy (Ancestors)

HypertensionVascular DiseasesCardiovascular Diseases

Study Officials

  • Guy AMAH, MD

    Service de Physiologie Clinique - Explorations Fonctionnelles

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 8, 2014

First Posted

October 29, 2014

Study Start

October 1, 2014

Primary Completion

July 1, 2015

Study Completion

July 1, 2015

Last Updated

May 22, 2015

Record last verified: 2014-10

Locations