NCT02272491

Brief Summary

The aim of the present study is to test whether or not the use of translucent monolithic zirconia crowns bonded to a titanium base abutment perform similar to porcelain-fused-to-metal crowns on single implants in the posterior region.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
83

participants targeted

Target at P50-P75 for not_applicable

Timeline
18mo left

Started Oct 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress89%
Oct 2014Nov 2027

Study Start

First participant enrolled

October 1, 2014

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

October 10, 2014

Completed
13 days until next milestone

First Posted

Study publicly available on registry

October 23, 2014

Completed
8.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 25, 2022

Completed
4.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2027

Expected
Last Updated

May 15, 2023

Status Verified

May 1, 2023

Enrollment Period

8.2 years

First QC Date

October 10, 2014

Last Update Submit

May 12, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Technical complication rate

    assessed by USPHS-criteria

    5 years

Secondary Outcomes (4)

  • Survival rate

    6-month, 1, 3, 5, 7, 10 years

  • Biological complication rate

    6-month, 1, 3, 5, 7, 10 years

  • Wear rate of the antagonist

    6-month, 1, 3, 5, 7, 10 years

  • Technical complication rate

    6-month, 1, 3 , 7, 10 years

Study Arms (2)

ZrO2

EXPERIMENTAL

1. Straumann CARES Variobase Abutment RN 2. Straumann CARES Full Contour Zerion HT The monolithic zircona crown (2) will be bonded to the titanium base (1)

Device: ZrO2 (Straumann CARES)

PFM crown

ACTIVE COMPARATOR

Straumann Gold Abutment RN Porcelain-fused-to-metal crown consisting of a gold abutment, a gold core, and veneering ceramic

Device: PFM crown (Straumann Gold)

Interventions

1. Straumann CARES Variobase Abutment RN 2. Straumann CARES Full Contour Zerion HT The monolithic zircona crown (2) will be bonded to the titanium base (1)

ZrO2

Porcelain-fused-to-metal crown consisting of a gold abutment, a gold core, and veneering ceramic

PFM crown

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Informed Consent as documented by signature
  • Male and female patients from 18-80 years of age
  • Presence of a Straumann Tissue Level implant with a regular platform (4.8 mm diameter platform) in the maxillary or mandibular molar region
  • Need for a single implant-supported crown
  • Implant position enabling screw-retained crown
  • Presence of antagonist

You may not qualify if:

  • Known or suspected non-compliance, drug or alcohol abuse
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant
  • Smoking more than 15 cigarettes a day
  • Poor oral hygiene (Plaque Index over 30%)
  • Bruxism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clinic of Reconstructive Dentistry

Zurich, 8032, Switzerland

Location

Study Officials

  • Alexis Ioannidis, Dr.

    Clinic of Reconstructive Dentistry

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 10, 2014

First Posted

October 23, 2014

Study Start

October 1, 2014

Primary Completion

November 25, 2022

Study Completion (Estimated)

November 1, 2027

Last Updated

May 15, 2023

Record last verified: 2023-05

Locations