NCT02271321

Brief Summary

The purpose of this study will be to examine the effects of white noise on agitation and saliva cortisol in elderly with dementia.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
84

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

October 15, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 22, 2014

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

October 22, 2014

Status Verified

October 1, 2014

Enrollment Period

2 years

First QC Date

October 15, 2014

Last Update Submit

October 21, 2014

Conditions

Keywords

dementiawhite noiseagitationsaliva cortisol

Outcome Measures

Primary Outcomes (1)

  • Improve the agitation behavior

    Agitation behavior will be assessed by Cohen-Mansfield Agitation Inventory (CMAI) including physically nonaggressive behavior (PNAB), physically aggressive behavior (PAGB), verbally nonaggressive behavior (VNAB) and verbally aggressive behavior (VAGB) at two different times: (1) baseline data :before white noise intervention, (2) outcome data: at four weeks post-test.

    Change from baseline in agitation behavior at 1 months

Secondary Outcomes (3)

  • Improve the cortisol homeostasis

    Change from baseline in saliva cortisol at 1 months

  • Improve quality of care

    Change from baseline in quality of care at 1 months

  • Basic attribute data

    Baseline

Study Arms (2)

control group

NO INTERVENTION

The control group will receive usual care

experimental group

EXPERIMENTAL

The experimental group will receive 20 minute white noise of the ocean and the sound of running water at 16:00 to 17:00 for four weeks periods.

Other: White noise

Interventions

White noise is a simple, convenient, non-invasive and effective intervention. it sounds like the sound of running water, ocean or fan operation sounds. In this study, Subjects will receive 20 minute white noise of the ocean and the sound of running water at 16:00 to 17:00 for four weeks periods.

experimental group

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • years and older
  • No hearing disorders
  • Able to communicate in Mandarin or Taiwanese
  • Able to attend the program and fill out inform consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Division of Core Laboratory; Chang Bing Show Chwan Memorial Hospital

Changhua County, Taiwan

RECRUITING

MeSH Terms

Conditions

DementiaPsychomotor Agitation

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental DisordersDyskinesiasNeurologic ManifestationsPsychomotor DisordersNeurobehavioral ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsAberrant Motor Behavior in DementiaBehavioral SymptomsBehavior

Study Officials

  • Li-Wei Lin, PhD.

    Department of Nursing, Hung Kuang University

    PRINCIPAL INVESTIGATOR
  • Shu-Hui Yeh, PhD.

    Chang Bing Show Chwan Memorial Hospital & Central Taiwan University of Science and Technology

    PRINCIPAL INVESTIGATOR
  • Li-Jane Tsai, M.S.

    Kuang Tien General Hospital

    PRINCIPAL INVESTIGATOR
  • Lu-Jen Tsai, M.S.

    Chang Bing Show Chwan Memorial Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Shu-Hui Yeh, PhD.

CONTACT

Kuender D. Yang, PhD.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
RN, PhD, Professor

Study Record Dates

First Submitted

October 15, 2014

First Posted

October 22, 2014

Study Start

November 1, 2013

Primary Completion

November 1, 2015

Study Completion

November 1, 2015

Last Updated

October 22, 2014

Record last verified: 2014-10

Locations