Cardiovascular Disease Population Risk Tool

NCT02267447 | Completed Results

• 1 other identifier: CIHR FRN - 133550
• Study Type: observational
• Target: 104,219
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to develop, evaluate, and apply a predictive algorithm for assessing CVD risk in the community setting: the Cardiovascular Disease Population Risk Tool (CVDPoRT).

Conditions

Cardiovascular Diseases

Keywords

Cardiovascular diseases; Clinical prediction rule; Population projection; Risk stratification; Health behavior

Outcome Measures

Primary Outcomes (1)

• Major Cardiovascular Disease Event

  The primary outcome of interest was a major CVD event resulting in hospitalization or sudden death from CVD. Respondents were followed from the survey administration date until the earliest of: incident event, death due to causes other than CVD (defined as a competing risk), loss to follow-up (defined as loss of health care eligibility), or end of study (31 December 2012).

  up to 12 years

Other Outcomes (1)

• Death Due to Causes Other Than CVD

  up to 12 years

Study Arms (2)

Derivation cohort

Eligible respondents to the combined 2001, 2003 and 2005 Canadian Community Health Surveys, conducted by Statistics Canada.

Validation cohort

Eligible respondents to the 2007 and 2009 Canadian Community Health Surveys.

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The derivation cohort will be eligible respondents to the combined 2001, 2003 and 2005 Canadian Community Health Surveys, conducted by Statistics Canada. The validation cohort will consist of respondents to the 2007 and 2009 surveys.

You may qualify if:

• Respondents to the Canadian Community Health Surveys

You may not qualify if:

• Not eligible for Ontario's universal health insurance program
• Pregnant
• Prior history of heart disease or stroke
• Younger than age 20

Sponsors & Collaborators

• Ottawa Hospital Research Institute: lead
• Canadian Institutes of Health Research (CIHR): collaborator
• Institute for Clinical Evaluative Sciences: collaborator
• Statistics Canada: collaborator

Related Publications (2)

• Manuel DG, Tuna M, Bennett C, Hennessy D, Rosella L, Sanmartin C, Tu JV, Perez R, Fisher S, Taljaard M. Development and validation of a cardiovascular disease risk-prediction model using population health surveys: the Cardiovascular Disease Population Risk Tool (CVDPoRT). CMAJ. 2018 Jul 23;190(29):E871-E882. doi: 10.1503/cmaj.170914.

  PMID: 30037888 DERIVED

• Taljaard M, Tuna M, Bennett C, Perez R, Rosella L, Tu JV, Sanmartin C, Hennessy D, Tanuseputro P, Lebenbaum M, Manuel DG. Cardiovascular Disease Population Risk Tool (CVDPoRT): predictive algorithm for assessing CVD risk in the community setting. A study protocol. BMJ Open. 2014 Oct 23;4(10):e006701. doi: 10.1136/bmjopen-2014-006701.

  PMID: 25341454 DERIVED

MeSH Terms

Conditions

Cardiovascular Diseases; Health Behavior

Condition Hierarchy (Ancestors)

Behavior

Results Point of Contact

• Title: Dr. Doug Manuel
• Organization: Ottawa Hospital Research Institute

dmanuel@ohri.ca

613-798-5555

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 6, 2014
• First Posted: October 17, 2014
• Study Start: September 1, 2000
• Primary Completion: December 1, 2014
• Study Completion: April 1, 2016
• Last Updated: August 7, 2017
• Results First Posted: August 7, 2017

Record last verified: 2017-04

Data Sharing

• IPD Sharing: Will share