NCT00010608

Brief Summary

The purpose of this study is to evaluate the effectiveness of meditation in preventing of atherosclerotic cardiovascular disease (CVD) in postmenopausal, older African American women.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P50-P75 for phase_2 cardiovascular-diseases

Timeline
Completed

Started Oct 1999

Longer than P75 for phase_2 cardiovascular-diseases

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 1999

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

February 2, 2001

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 5, 2001

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2006

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2006

Completed
Last Updated

December 7, 2009

Status Verified

December 1, 2009

Enrollment Period

6.8 years

First QC Date

February 2, 2001

Last Update Submit

December 4, 2009

Conditions

Keywords

CVD

Outcome Measures

Primary Outcomes (1)

  • Carotid artery atherosclerosis (IMT) measured non-invasively by quantitative B-mode ultrasonography

    one year

Study Arms (2)

Transcendental Meditation program

EXPERIMENTAL

A mental technique for stress reduction which is natural, easy and effortless and is practiced sitting in a chair with eyes closed for 20 minutes twice a day.

Behavioral: Transcendental Meditation

Health Education

ACTIVE COMPARATOR

A lifestyle modification program for improving diet, exercise, salt intake and substance use.

Behavioral: Health Education

Interventions

a mantra meditation technique which originated from the Vedic tradition of India. It is practiced from 20 minutes twice a day sitting comfortably in a chair with eyes closed.

Transcendental Meditation program

didactic education classes for lifestyle modification through diet, exercise, substance use control, and salt intake

Health Education

Eligibility Criteria

Age60 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • African American, self-identified
  • Coronary artery disease (CAD/CHD) defined by laboratory examination or documented clinical history of: a)myocardial infarction; b) coronary revascularization procedure--CABG, PTCA; c) coronary angiography--at least one coronary artery with \>50% stenosis
  • Informed consent
  • Written Permission of participant's referring physician

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Howard University Medical Center

Washington D.C., District of Columbia, United States

Location

Morehouse School of Medicine

Atlanta, Georgia, United States

Location

Maharishi University of Management

Fairfield, Iowa, 52557, United States

Location

MeSH Terms

Conditions

Cardiovascular Diseases

Interventions

Meditation

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesRelaxation TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Robert H. Schneider, MD

    Center for Health and Aging Studies

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
NIH

Study Record Dates

First Submitted

February 2, 2001

First Posted

February 5, 2001

Study Start

October 1, 1999

Primary Completion

July 1, 2006

Study Completion

July 1, 2006

Last Updated

December 7, 2009

Record last verified: 2009-12

Locations