NCT02266615

Brief Summary

Collection of coded biomaterial and clinical data with patients consent for future research.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,600

participants targeted

Target at P75+ for all trials

Timeline
106mo left

Started Sep 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress57%
Sep 2014Jan 2035

Study Start

First participant enrolled

September 1, 2014

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

September 18, 2014

Completed
29 days until next milestone

First Posted

Study publicly available on registry

October 17, 2014

Completed
9.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
10.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2035

Expected
Last Updated

October 6, 2025

Status Verified

May 1, 2025

Enrollment Period

9.5 years

First QC Date

September 18, 2014

Last Update Submit

October 2, 2025

Conditions

Genetic Disease

Outcome Measures

Primary Outcomes (1)

  • Comparing genes to discover unknown functions

    The biobanked bio material and medical data can be used for future research to learn more about the function of genes.

    Genes will be sequenced and compared, within an expected average of 6 months.

Study Arms (1)

Genetic research in 5 areas.

Cardiogenetics; Intellectual Disability, Multiple Congenital Abnormalities and Rare Diseases; Oncogenetics; Dermatogenetics; Reproductive Genetics.

Genetic: Biobanking of biomaterial for future genetic research.

Interventions

Biobanking of biomaterial for future genetic research.GENETIC
Genetic research in 5 areas.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

New patients visiting the out patient clinic of the department of Clinical Genetics of the Maastricht University Medical Hospital and who get blood or tissue sampled for DNA diagnostics.

You may qualify if:

  • New patients visiting the out patient clinic of the department of Clinical Genetics of the Maastricht University Medical Hospital
  • Withdrawal of body material for genetic diagnostics.

You may not qualify if:

  • Patient does not understand the Dutch language.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maastricht University Medical Center

Maastricht, Limburg, 6229 HV, Netherlands

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

DNA retrieved out of blood or tissue

MeSH Terms

Conditions

Genetic Diseases, Inborn

Condition Hierarchy (Ancestors)

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • W. van Zelst-Stams, MD, PhD

    Head of department

    STUDY DIRECTOR

Central Study Contacts

I. Krapels, MD, PhD

CONTACT

+31433875880ingrid.krapels@mumc.nl

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 18, 2014

First Posted

October 17, 2014

Study Start

September 1, 2014

Primary Completion

March 1, 2024

Study Completion (Estimated)

January 1, 2035

Last Updated

October 6, 2025

Record last verified: 2025-05

Locations

NL(1)