NCT02261194

Brief Summary

The purpose of this trial is to determine the short-term effect of a self-care intervention on depression in patients with age-related macular degeneration or diabetic retinopathy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P25-P50 for not_applicable depression

Timeline
Completed

Started Oct 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

October 2, 2014

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 10, 2014

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2016

Completed
Last Updated

November 15, 2016

Status Verified

November 1, 2016

Enrollment Period

1.3 years

First QC Date

October 2, 2014

Last Update Submit

November 14, 2016

Conditions

Keywords

depressionage-related macular degenerationself-careself-help

Outcome Measures

Primary Outcomes (1)

  • Change in depressive symptoms

    Depressive symptoms will be measured by the PHQ-9, a validated 9 item instrument.

    Baseline and 8 weeks

Secondary Outcomes (3)

  • Change in severity of anxiety symptoms

    Baseline and 8 weeks

  • Change in self-efficacy

    Baseline and 8 weeks

  • Change in life space

    Baseline and 8 weeks

Study Arms (2)

Self-Care Tools

EXPERIMENTAL

The tool binder includes 3 core tools and 4 supplemental tools. The tools that will be provided include a variety of self-care approaches to manage depression including audio-visual, internet, and paper-based tools that might appeal to individuals with different learning styles. The 3 core tools consist of the Antidepressant Skills Workbook, a Mood Monitoring Tool, and a DVD on depression.

Behavioral: Self-Care Tools

Delayed Self-Care Tools

NO INTERVENTION

This group will receive the self-care tools at the conclusion of the study.

Interventions

Self-Care ToolsBEHAVIORAL
Self-Care Tools

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • clinical diagnosis of wet or dry AMD or diabetic retinopathy
  • age 50 years and older
  • at least mild depressive symptoms (a score of 5 or more on the PHQ-9)
  • no legal blindness (visual acuity better than 20/200 in better eye).

You may not qualify if:

  • the current use of cognitive behavioural therapy
  • suicidal intent
  • ocular surgery during the study period (intravitreal anti-VEGF injections will be allowed, e.g. Lucentis)
  • cognitive impairment
  • inability to speak and understand French or English
  • profound hearing impairment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maisonneuve-Rosemont Hospital

Montreal, Quebec, H1T2M4, Canada

Location

MeSH Terms

Conditions

DepressionMacular Degeneration

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorRetinal DegenerationRetinal DiseasesEye Diseases

Study Officials

  • Ellen E. Freeman, PhD

    Maisonneuve-Rosemont Hospital and University of Montreal

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 2, 2014

First Posted

October 10, 2014

Study Start

October 1, 2014

Primary Completion

February 1, 2016

Study Completion

February 1, 2016

Last Updated

November 15, 2016

Record last verified: 2016-11

Locations