Trials Sponsors Conditions Drugs Pricing

Conditions

Chronic Tic Disorder Tourette Syndrome

Keywords

Tourette Syndrometic disordersbehavior therapyweb-based videoconferencingVoIP

Outcome Measures

Primary Outcomes (1)

Change from baseline in Yale Global Tic Severity Scale (YGTSS) total tic severity scores at 10 weeks
The YGTSS is a clinician-rated tic severity measure, featuring a total severity score, with a rating from 0 to 50, and independent subtotals for motor and vocal tics each with ratings from 0 to 25. It also features a tic-related 0-50 point impairment scale.
Baseline, 10-week (post-treatment)

Secondary Outcomes (2)

Change from baseline on the Clinical Global Impressions-Severity scale at 10 weeks
Baseline, 10-week (post-treatment)
Treatment response rate using the Clinical Global Impressions-Improvement scale at 10 weeks
10-week (post-treatment)

Study Arms (2)

Behavior Therapy for Tics (CBIT)

EXPERIMENTAL

The child 1) learns to become more aware of any sensations, or urges that may trigger tics, and 2) learn some other behavior (competing response) to do every time he/she feels the urge to tic. The child's parent is trained to provide prompts and praise for use of the competing response. The parent and family also receive psychoeducation about tics, and learn ways to reduce the impact of environmental stimuli on tic severity. The child learns relaxation techniques to reduce stress and make it easier for him/her to resist his or her tics. Prior to treatment sessions, the parent and child spend about 10 minutes discussing with the therapist any problematic issues he/she is having. At the end of treatment sessions the child is assigned some tasks to practice prior to the next session.

Behavioral: Behavior Therapy for Tics (CBIT)

Waitlist-control Group

NO INTERVENTION

Participants in the waitlist-control group, do not receive behavior therapy for tics or any other treatment during the 10-week acute treatment period. Instead they child are placed on a waitlist to receive videoconference-delivered treatment following the end of the study period.

Interventions

Behavior Therapy for Tics (CBIT)Behavioral

CBIT is an 8-session 10-week behavioral treatment for chronic tic disorders, including Tourette Syndrome. The first two sessions are 90 minutes, with subsequent sessions lasting 60 minutes. The treatment consists of Habit Reversal Training (awareness training, competing response training, and social support), and function-based assessment to reduce the impact of environmental or other stimuli on tic severity. The treatment also consists of relaxation techniques to reduce tic-related stress and tension, and behavioral rewards to motivate treatment compliance.

Also known as: Comprehensive Behavioral Intervention for Tics (CBIT), Habit Reversal Training (HRT)

Behavior Therapy for Tics (CBIT)

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age8 Years - 17 Years

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17)

You may qualify if:

Resides in the state of Wisconsin
Ages 8-17

Sponsors & Collaborators

University of Wisconsin, Milwaukee
Otherlead
National Institute of Mental Health (NIMH)
NIHcollaborator
University of Utah

Study Sites (1)

University of Wisconsin-Milwaukee Psychology Department

Milwaukee, Wisconsin, 53211, United States

MeSH Terms

Conditions

Tourette SyndromeTic Disorders

Interventions

Behavior Therapy

Condition Hierarchy (Ancestors)

Basal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersHeredodegenerative Disorders, Nervous SystemNeurodegenerative DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNeurodevelopmental Disorders

Study Officials

Emily J Ricketts, PhD
University of Wisconsin, Milwaukee
PRINCIPAL INVESTIGATOR
Douglas W Woods, PhD
Texas A&M University
STUDY DIRECTOR
Michael B Himle, PhD
University of Utah
STUDY CHAIR

Enrollment

20 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: phase 2
Allocation: RANDOMIZED
Masking: SINGLE
Who Masked: OUTCOMES ASSESSOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Doctoral Student

Study Record Dates

First Submitted

September 15, 2014

First Posted

September 23, 2014

Study Start

December 2012

Date type not reported

This date has not been verified as actual or estimated.

VoIP Delivered Behavior Therapy for Tourette Syndrome

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

Behavior Therapy for Tics (CBIT)

Waitlist-control Group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (2)

Study Arms (2)

Behavior Therapy for Tics (CBIT)

Waitlist-control Group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Intervention Hierarchy (Ancestors)

Source record

Locations